Basal ganglia play a central role in regulating behavior, but the organization of their outputs
to other brain areas is incompletely understood. We investigate the largest output nucleus …

Cognitive processes involve precisely coordinated neuronal communications between
multiple cerebral cortical structures in a task specific manner. Rich new evidence now …

The cerebellum is known to make movements fast, smooth, and accurate. Many hypotheses
emphasize the role of the cerebellum in computing learned predictions important for …

Corticospinal pyramidal neurons mediate diverse aspects of motor behavior. We measured
spike-related electrophysiological properties of identified corticospinal neurons in primary …

Identification of marker genes expressed in specific cell types is essential for the genetic
dissection of neural circuits. Here we report a new strategy for classifying heterogeneous …

The survival of vertebrates is dependent on maintaining their body equilibrium in the
gravitational field and being capable of orienting themselves in their environment. Studies …

The vast expansion from mossy fibers to cerebellar granule cells (GrC) produces a neural
representation that supports functions including associative and internal model learning …

Computations that require speed and temporal precision are implemented throughout the
nervous system by neurons capable of firing at very high rates, rapidly encoding and …

Key points Large premotor neurons of the cerebellar nuclei (CbN cells) integrate synaptic
inhibition from Purkinje neurons and synaptic excitation from mossy fibres to generate …

Combinatorial expansion by the cerebellar granule cell layer (GCL) is fundamental to
theories of cerebellar contributions to motor control and learning. Granule cells (GrCs) …