The Japanese clinical practice guidelines for management of sepsis and septic shock 2020 (J-SSCG 2020)

M Egi, H Ogura, T Yatabe, K Atagi, S Inoue, T Iba… - Journal of intensive …, 2021 - Springer
Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …

Fever of unknown origin

G Haidar, N Singh - New England Journal of Medicine, 2022 - Mass Medical Soc
Fever of Unknown Origin FUO despite a high-quality workup after a reasonable amount of
time has elapsed to rule out self-limited fevers remains a challenge. The clinician must pay …

Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children

SL Weiss, MJ Peters, W Alhazzani, MSD Agus… - Intensive care …, 2020 - Springer
Objectives To develop evidence-based recommendations for clinicians caring for children
(including infants, school-aged children, and adolescents) with septic shock and other …

The pathophysiological basis and consequences of fever

EJ Walter, S Hanna-Jumma, M Carraretto, L Forni - Critical Care, 2016 - Springer
There are numerous causes of a raised core temperature. A fever occurring in sepsis may
be associated with a survival benefit. However, this is not the case for non-infective triggers …

The neurological and cognitive consequences of hyperthermia

EJ Walter, M Carraretto - Critical Care, 2016 - Springer
An elevated temperature has many aetiologies, both infective and non-infective, and while
the fever of sepsis probably confers benefit, there is increasing evidence that the central …

The Japanese clinical practice guidelines for management of sepsis and septic shock 2016 (J-SSCG 2016)

O Nishida, H Ogura, M Egi, S Fujishima… - Journal of intensive …, 2018 - Springer
Abstract Background and purpose The Japanese Clinical Practice Guidelines for
Management of Sepsis and Septic Shock 2016 (J-SSCG 2016), a Japanese-specific set of …

Fever is associated with reduced, hypothermia with increased mortality in septic patients: a meta-analysis of clinical trials

Z Rumbus, R Matics, P Hegyi, C Zsiboras, I Szabo… - PloS one, 2017 - journals.plos.org
Background Sepsis is usually accompanied by changes of body temperature (Tb), but
whether fever and hypothermia predict mortality equally or differently is not fully clarified. We …

Fever and sickness behavior: friend or foe?

LM Harden, S Kent, QJ Pittman, J Roth - Brain, behavior, and immunity, 2015 - Elsevier
Fever has been recognized as an important symptom of disease since ancient times. For
many years, fever was treated as a putative life-threatening phenomenon. More recently, it …

Fever and hypothermia in systemic inflammation

A Garami, AA Steiner, AA Romanovsky - handbook of clinical neurology, 2018 - Elsevier
Systemic inflammation-associated syndromes (eg, sepsis and septic shock) often have high
mortality and remain a challenge in emergency medicine. Systemic inflammation is usually …

Prostaglandin E2 constrains systemic inflammation through an innate lymphoid cell–IL-22 axis

R Duffin, RA O'Connor, S Crittenden, T Forster, C Yu… - Science, 2016 - science.org
Systemic inflammation, which results from the massive release of proinflammatory
molecules into the circulatory system, is a major risk factor for severe illness, but the precise …