The ability of chemical modifications of single nucleotides to alter the electrostatic charge,
hydrophobic surface and base pairing of RNA molecules is exploited for the clinical use of …

RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

The ability to sense and respond to infection is essential for life. Viral infection produces
double-stranded RNAs (dsRNAs) that are sensed by proteins that recognize the structure of …

Effective immunity requires the innate immune system to distinguish foreign nucleic acids
from cellular ones. Cellular double-stranded RNAs (dsRNAs) are edited by the RNA-editing …

With the increasing availability of single-cell transcriptomes, RNA signatures offer a
promising basis for targeting living cells. Molecular RNA sensors would enable the study of …

RNA modifications, known as the “epitranscriptome”, represent a key layer of regulation that
influences a wide array of biological processes in mesenchymal stem cells (MSCs). These …

Chemical RNA modifications, collectively referred to as the “epitranscriptome,” are essential
players in fine-tuning gene expression. Our ability to analyze RNA modifications has …

Long noncoding RNAs (lncRNAs) are usually 5′ capped and 3′ polyadenylated, similar to
most typical mRNAs. However, recent studies revealed a type of snoRNA-related lncRNA …

RNA is not always a faithful copy of DNA. Advances in tools enabling the interrogation of the
exact RNA sequence have permitted revision of how genetic information is transferred. We …

Adar null mutant mouse embryos die with aberrant double-stranded RNA (dsRNA)-driven
interferon induction, and Adar Mavs double mutants, in which interferon induction is …