[HTML][HTML] Essential role of calcium in extending RTX adhesins to their target

TDR Vance, Q Ye, B Conroy, PL Davies - Journal of Structural Biology: X, 2020 - Elsevier
RTX adhesins are long, multi-domain proteins present on the outer membrane of many
Gram-negative bacteria. From this vantage point, adhesins use their distal ligand-binding …

[HTML][HTML] Molecular basis for inhibition of adhesin-mediated bacterial-host interactions through a peptide-binding domain

S Guo, H Zahiri, C Stevens, DC Spaanderman… - Cell Reports, 2021 - cell.com
Infections typically begin with pathogens adhering to host cells. For bacteria, this adhesion
can occur through specific ligand-binding domains. We identify a 20-kDa peptide-binding …

Prediction of Ca2+ Binding Site in Proteins With a Fast and Accurate Method Based on Statistical Mechanics and Analysis of Crystal Structures

A Basit, D Choudhury… - … : Structure, Function, and …, 2024 - Wiley Online Library
Predicting the precise locations of metal binding sites within metalloproteins is a crucial
challenge in biophysics. A fast, accurate, and interpretable computational prediction method …