The emerging role of epigenetics in therapeutic targeting of cardiomyopathies
C Pagiatakis, V Di Mauro - International Journal of Molecular Sciences, 2021 - mdpi.com
Cardiomyopathies (CMPs) are a heterogeneous group of myocardial diseases accountable
for the majority of cases of heart failure (HF) and/or sudden cardiac death (SCD) worldwide …
for the majority of cases of heart failure (HF) and/or sudden cardiac death (SCD) worldwide …
Calcium as a key player in arrhythmogenic cardiomyopathy: adhesion disorder or intracellular alteration?
Arrhythmogenic cardiomyopathy (ACM) is an inherited heart disease characterized by
sudden death in young people and featured by fibro-adipose myocardium replacement …
sudden death in young people and featured by fibro-adipose myocardium replacement …
Excess TGF-β1 drives cardiac mesenchymal stromal cells to a pro-fibrotic commitment in arrhythmogenic cardiomyopathy
Arrhythmogenic Cardiomyopathy (ACM) is characterized by the replacement of the
myocardium with fibrotic or fibro-fatty tissue and inflammatory infiltrates in the heart. To date …
myocardium with fibrotic or fibro-fatty tissue and inflammatory infiltrates in the heart. To date …
Oxidized LDL‐dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy
E Sommariva, I Stadiotti, M Casella, V Catto… - EMBO Molecular …, 2021 - embopress.org
Arrhythmogenic cardiomyopathy (ACM) is hallmarked by ventricular fibro‐adipogenic
alterations, contributing to cardiac dysfunctions and arrhythmias. Although genetically …
alterations, contributing to cardiac dysfunctions and arrhythmias. Although genetically …
Differential role of circulating microRNAs to track progression and pre-symptomatic stage of chronic heart failure: a pilot study
Y D'Alessandra, M Chiesa, MC Carena, AP Beltrami… - Biomedicines, 2020 - mdpi.com
(1) Background: Chronic heart failure (CHF) contributes to the overall burden of
cardiovascular disease. Early identification of at-risk individuals may facilitate the targeting …
cardiovascular disease. Early identification of at-risk individuals may facilitate the targeting …
The time has come to explore plasma biomarkers in genetic cardiomyopathies
NM Stege, RA de Boer, MP van den Berg… - International Journal of …, 2021 - mdpi.com
For patients with hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM) or
arrhythmogenic cardiomyopathy (ACM), screening for pathogenic variants has become …
arrhythmogenic cardiomyopathy (ACM), screening for pathogenic variants has become …
Fibrosis in arrhythmogenic cardiomyopathy: the phantom thread in the fibro-adipose tissue
Arrhythmogenic cardiomyopathy (ACM) is an inherited heart disorder, predisposing to
malignant ventricular arrhythmias leading to sudden cardiac death, particularly in young and …
malignant ventricular arrhythmias leading to sudden cardiac death, particularly in young and …
Cardiac biomarkers and autoantibodies in endurance athletes: Potential similarities with arrhythmogenic cardiomyopathy pathogenic mechanisms
The “Extreme Exercise Hypothesis” states that when individuals perform training beyond the
ideal exercise dose, a decline in the beneficial effects of physical activity occurs. This is due …
ideal exercise dose, a decline in the beneficial effects of physical activity occurs. This is due …
MicroRNA composition of plasma extracellular vesicles: a harbinger of late cardiotoxicity of doxorubicin
J Totoń-Żurańska, J Sulicka-Grodzicka, MT Seweryn… - Molecular …, 2022 - Springer
Background The use of doxorubicin is associated with an increased risk of acute and long-
term cardiomyopathy. Despite the constantly growing number of cancer survivors, little is …
term cardiomyopathy. Despite the constantly growing number of cancer survivors, little is …
The role of microRNAs in arrhythmogenic cardiomyopathy: biomarkers or innocent bystanders of disease progression?
Arrhythmogenic cardiomyopathy (AC) is an inherited cardiac disease characterized by a
progressive fibro-fatty replacement of the working myocardium and by life-threatening …
progressive fibro-fatty replacement of the working myocardium and by life-threatening …