The life stage‐specific pathometabolism of Legionella pneumophila

W Eisenreich, K Heuner - FEBS letters, 2016 - Wiley Online Library
The genus Legionella belongs to Gram‐negative bacteria found ubiquitously in aquatic
habitats, where it grows in natural biofilms and replicates intracellularly in various protozoa …

Rapid fucosylation of intestinal epithelium sustains host–commensal symbiosis in sickness

JM Pickard, CF Maurice, MA Kinnebrew, MC Abt… - Nature, 2014 - nature.com
Systemic infection induces conserved physiological responses that include both resistance
and 'tolerance of infection'mechanisms. Temporary anorexia associated with an infection is …

Nutrient salvaging and metabolism by the intracellular pathogen Legionella pneumophila

MV Fonseca, MS Swanson - Frontiers in cellular and infection …, 2014 - frontiersin.org
The Gram-negative bacterium Legionella pneumophila is ubiquitous in freshwater
environments as a free-swimming organism, resident of biofilms, or parasite of protozoa. If …

Comparative Genomics of Wolbachia and the Bacterial Species Concept

KM Ellegaard, L Klasson, K Näslund, K Bourtzis… - PLoS …, 2013 - journals.plos.org
The importance of host-specialization to speciation processes in obligate host-associated
bacteria is well known, as is also the ability of recombination to generate cohesion in …

Legionella Pneumophila Transcriptome during Intracellular Multiplication in Human Macrophages

SP Faucher, CA Mueller, HA Shuman - Frontiers in microbiology, 2011 - frontiersin.org
Legionella pneumophila is the causative agent of Legionnaires' disease, an acute
pulmonary infection. L. pneumophila is able to infect and multiply in both phagocytic …

Transcriptional Profiling of Coxiella burnetii Reveals Extensive Cell Wall Remodeling in the Small Cell Variant Developmental Form

KM Sandoz, DL Popham, PA Beare, DE Sturdevant… - PloS one, 2016 - journals.plos.org
A hallmark of Coxiella burnetii, the bacterial cause of human Q fever, is a biphasic
developmental cycle that generates biologically, ultrastructurally, and compositionally …

Complementation of arginine auxotrophy for genetic transformation of Coxiella burnetii by use of a defined axenic medium

KM Sandoz, PA Beare, DC Cockrell… - Applied and …, 2016 - Am Soc Microbiol
Host cell-free (axenic) culture of Coxiella burnetii in acidified citrate cysteine medium-2
(ACCM-2) has provided important opportunities for investigating the biology of this naturally …

Experimental Evolution of Legionella pneumophila in Mouse Macrophages Leads to Strains with Altered Determinants of Environmental Survival

AW Ensminger, Y Yassin, A Miron, RR Isberg - PLoS Pathogens, 2012 - journals.plos.org
The Gram-negative bacterium, Legionella pneumophila, is a protozoan parasite and
accidental intracellular pathogen of humans. We propose a model in which cycling through …

Sequencing Illustrates the Transcriptional Response of Legionella pneumophila during Infection and Identifies Seventy Novel Small Non-Coding RNAs

BA Weissenmayer, JGD Prendergast, AJ Lohan… - PloS one, 2011 - journals.plos.org
Second generation sequencing has prompted a number of groups to re-interrogate the
transcriptomes of several bacterial and archaeal species. One of the central findings has …

Metabolism of the vacuolar pathogen Legionella and implications for virulence

C Manske, H Hilbi - Frontiers in cellular and infection microbiology, 2014 - frontiersin.org
Legionella pneumophila is a ubiquitous environmental bacterium that thrives in fresh water
habitats, either as planktonic form or as part of biofilms. The bacteria also grow intracellularly …