Brain asymmetries from mid-to late life and hemispheric brain age

M Korbmacher, D van der Meer, D Beck… - Nature …, 2024 - nature.com
The human brain demonstrates structural and functional asymmetries which have
implications for ageing and mental and neurological disease development. We used a set of …

Bio-psycho-social factors' associations with brain age: a large-scale UK Biobank diffusion study of 35,749 participants

M Korbmacher, TP Gurholt, AMG de Lange… - Frontiers in …, 2023 - frontiersin.org
Brain age refers to age predicted by brain features. Brain age has previously been
associated with various health and disease outcomes and suggested as a potential …

Probing evidence of cerebral white matter microstructural disruptions in ischemic heart disease before and following cardiac rehabilitation: A diffusion tensor MR …

SE Poirier, NG Suskin, AV Khaw… - Journal of Magnetic …, 2024 - Wiley Online Library
Background Ischemic heart disease (IHD) is linked to brain white matter (WM) breakdown
but how age or disease effects WM integrity, and whether it is reversible using cardiac …

Considerations on brain age predictions from repeatedly sampled data across time

M Korbmacher, MY Wang, R Eikeland… - Brain and …, 2023 - Wiley Online Library
Introduction Brain age, the estimation of a person's age from magnetic resonance imaging
(MRI) parameters, has been used as a general indicator of health. The marker requires …

Unique information from common diffusion MRI models about white-matter differences across the human adult lifespan

RN Henriques, R Henson, Cam-CAN… - Imaging …, 2023 - direct.mit.edu
Abstract Diffusion Magnetic Resonance Imaging (dMRI) is sensitive to white matter
microstructural changes across the human lifespan. Several models have been proposed to …

[HTML][HTML] Distinct longitudinal brain white matter microstructure changes and associated polygenic risk of common psychiatric disorders and Alzheimer's disease in the …

M Korbmacher, D van der Meer, D Beck… - … Psychiatry Global Open …, 2024 - Elsevier
Background During the course of adulthood and aging, white matter (WM) structure and
organization are characterized by slow degradation processes such as demyelination and …

Choir singing is associated with enhanced structural connectivity across the adult lifespan

N Moisseinen, L Ahveninen… - Human Brain …, 2024 - Wiley Online Library
The global ageing of populations calls for effective, ecologically valid methods to support
brain health across adult life. Previous evidence suggests that music can promote white …

Associations between adiposity and white matter hyperintensities: Cross‐sectional and longitudinal analyses of 34,653 participants

RZ Wang, YT Deng, W Zhang, J Ning… - Human Brain …, 2024 - Wiley Online Library
Objectives White matter hyperintensities (WMH) increase the risk of stroke and cognitive
impairment. This study aims to determine the cross‐sectional and longitudinal associations …

[HTML][HTML] Senescent and disease-associated microglia are modifiable features of aged brain white matter

CM Carver, PT Gomez, SL Rodriguez… - Research …, 2023 - ncbi.nlm.nih.gov
Brain white matter tracts undergo structural and functional changes linked to late-life
cognitive decline, but the cellular and molecular contributions to their selective vulnerability …

Rate of brain aging associates with future executive function in Asian children and older adults

SF Cheng, WL Yue, KK Ng, X Qian, S Liu, TWK Tan… - bioRxiv, 2023 - biorxiv.org
Brain age has emerged as a powerful tool to understand neuroanatomical aging and its link
to health outcomes like cognition. However, most brain age models are trained and tested …