Wolbachia as translational science: controlling mosquito-borne pathogens

EP Caragata, HLC Dutra, PHF Sucupira… - Trends in …, 2021 - cell.com
In this review we examine how exploiting the Wolbachia–mosquito relationship has become
an increasingly popular strategy for controlling arbovirus transmission. Field deployments of …

Translational regulation by ribosome-associated quality control in neurodegenerative disease, cancer, and viral infection

B Lu - Frontiers in cell and developmental biology, 2022 - frontiersin.org
Translational control at the initiation, elongation, and termination steps exerts immediate
effects on the rate as well as the spatiotemporal dynamics of new protein synthesis, shaping …

A recessive gene pepy-1 encoding Pelota confers resistance to begomovirus isolates of PepYLCIV and PepYLCAV in Capsicum annuum

S Koeda, M Onouchi, N Mori, NS Pohan… - Theoretical and Applied …, 2021 - Springer
Key message A begomovirus resistance gene pepy-1, which encodes the messenger RNA
surveillance factor Pelota, was identified in pepper (C. annuum) through map-based cloning …

Zika virus and temperature modulate Elizabethkingia anophelis in Aedes albopictus

MG Onyango, R Lange, S Bialosuknia, A Payne… - Parasites & …, 2021 - Springer
Background Vector-borne pathogens must survive and replicate in the hostile environment
of an insect's midgut before successful dissemination. Midgut microbiota interfere with …

Wolbachia RNase HI contributes to virus blocking in the mosquito Aedes aegypti

M Hussain, G Zhang, M Leitner, LM Hedges, S Asgari - IScience, 2023 - cell.com
The endosymbiotic bacterium Wolbachia pipientis blocks replication of several arboviruses
in transinfected Aedes aegypti mosquitoes. However, the mechanism of virus blocking …

MicroRNAs reshape the immunity of insects in response to bacterial infection

MN Abbas, S Kausar, B Asma, W Ran, J Li… - Frontiers in …, 2023 - frontiersin.org
The interaction between bacteria and insects can significantly impact a wide range of
different areas because bacteria and insects are widely distributed around the globe. The …

ty-5 Confers Broad-Spectrum Resistance to Geminiviruses

Y Ren, X Tao, D Li, X Yang, X Zhou - Viruses, 2022 - mdpi.com
The selection of resistant crops is an effective method for controlling geminivirus diseases. ty-
5 encodes a messenger RNA surveillance factor Pelota with a single amino acid mutation …

A comprehensive review of Wolbachia-mediated mechanisms to control dengue virus transmission in Aedes aegypti through innate immune pathways

I Mushtaq, MS Sarwar, I Munzoor - Frontiers in Immunology, 2024 - frontiersin.org
The Dengue virus (DENV), primarily spread by Aedes aegypti and also by Aedes albopictus
in some regions, poses significant global health risks. Alternative techniques are urgently …

A role for the insulin receptor in the suppression of dengue virus and Zika virus in Wolbachia-infected mosquito cells

G Haqshenas, G Terradas, PN Paradkar, JB Duchemin… - Cell Reports, 2019 - cell.com
Wolbachia-infected mosquitoes are refractory to super-infection with arthropod-borne
pathogens, but the role of host cell signaling proteins in pathogen-blocking mechanisms …

Pharmacological potential of ants and their symbionts–a review

S Agarwal, G Sharma, K Verma… - Entomologia …, 2022 - Wiley Online Library
Abstract Ants (Hymenoptera: Formicidae) play an important role in the pharmacological and
food industry due to their therapeutic and nutritional properties. Being the most abundant …