M Bravo, T Dileepan, M Dolan, J Hildebrand… - The Journal of …, 2024 - journals.aai.org
Malaria, which results from infection with Plasmodium parasites, remains a major public health problem. Although humans do not develop long-lived, sterilizing immunity, protection …
JM Sattler, L Keiber, A Abdelrahim, X Zheng… - EMBO molecular …, 2024 - embopress.org
Malaria vaccination approaches using live Plasmodium parasites are currently explored, with either attenuated mosquito-derived sporozoites or attenuated blood-stage parasites …
CK Cimperman, M Pena, SM Gokcek, BP Theall… - MBio, 2023 - Am Soc Microbiol
Cerebral malaria (CM), the deadliest complication of Plasmodium infection, is a complex and unpredictable disease. However, our understanding of the host and parasite factors that …
CRISPR/Cas systems are popular genome editing tools that belong to a class of programmable nucleases and have enabled tremendous progress in the field of …
The increased resistance of Plasmodium falciparum to artemisinin and its partner drugs poses a serious challenge to global malaria control and elimination programs. This study …
A Georgiadou, C Dunican, P Soro-Barrio, HJ Lee… - Elife, 2022 - elifesciences.org
Recent initiatives to improve translation of findings from animal models to human disease have focussed on reproducibility but quantifying the relevance of animal models remains a …
E Quansah, J Zhao, KK Eduful, EK Amoako… - Parasites & …, 2024 - Springer
Abstract Background Pf AP2-EXP2 is located within chromosome 6 of Plasmodium falciparum recently identified to be undergoing an extensive selective sweep in West African …
PC Cabral, J Weinerman, M Olivier, N Cermakian - Iscience, 2024 - cell.com
Malaria is a disease caused by infection with parasite Plasmodium spp. We studied the circadian regulation of host responses to the parasite, in a mouse model of cerebral malaria …