The origins, isolation, and biological characterization of rodent malaria parasites

S Pattaradilokrat, J Wu, F Xu, X Su - Parasitology international, 2022 - Elsevier
Rodent malaria parasites have been widely used in all aspects of malaria research to study
parasite development within rodent and insect hosts, drug resistance, disease …

IL-15 Complex–Induced IL-10 Enhances Plasmodium-specific CD4+ T Follicular Helper Differentiation and Antibody Production

M Bravo, T Dileepan, M Dolan, J Hildebrand… - The Journal of …, 2024 - journals.aai.org
Malaria, which results from infection with Plasmodium parasites, remains a major public
health problem. Although humans do not develop long-lived, sterilizing immunity, protection …

Experimental vaccination by single dose sporozoite injection of blood-stage attenuated malaria parasites

JM Sattler, L Keiber, A Abdelrahim, X Zheng… - EMBO molecular …, 2024 - embopress.org
Malaria vaccination approaches using live Plasmodium parasites are currently explored,
with either attenuated mosquito-derived sporozoites or attenuated blood-stage parasites …

Cerebral Malaria Is Regulated by Host-Mediated Changes in Plasmodium Gene Expression

CK Cimperman, M Pena, SM Gokcek, BP Theall… - MBio, 2023 - Am Soc Microbiol
Cerebral malaria (CM), the deadliest complication of Plasmodium infection, is a complex
and unpredictable disease. However, our understanding of the host and parasite factors that …

[HTML][HTML] Disease modeling and stem cell immunoengineering in regenerative medicine using CRISPR/Cas9 systems

AM Antao, JK Karapurkar, DR Lee, KS Kim… - Computational and …, 2020 - Elsevier
CRISPR/Cas systems are popular genome editing tools that belong to a class of
programmable nucleases and have enabled tremendous progress in the field of …

Exploring the potential antimalarial properties, safety profile, and phytochemical composition of Mesua ferrea Linn.

A Konyanee, P Chaniad, A Phuwajaroanpong, W Plirat… - Plos one, 2024 - journals.plos.org
The increased resistance of Plasmodium falciparum to artemisinin and its partner drugs
poses a serious challenge to global malaria control and elimination programs. This study …

Comparative transcriptomic analysis reveals translationally relevant processes in mouse models of malaria

A Georgiadou, C Dunican, P Soro-Barrio, HJ Lee… - Elife, 2022 - elifesciences.org
Recent initiatives to improve translation of findings from animal models to human disease
have focussed on reproducibility but quantifying the relevance of animal models remains a …

Low nucleotide diversity of the Plasmodium falciparum AP2-EXP2 gene among clinical samples from Ghana

E Quansah, J Zhao, KK Eduful, EK Amoako… - Parasites & …, 2024 - Springer
Abstract Background Pf AP2-EXP2 is located within chromosome 6 of Plasmodium
falciparum recently identified to be undergoing an extensive selective sweep in West African …

Time of day and circadian disruption influence host response and parasite growth in a mouse model of cerebral malaria

PC Cabral, J Weinerman, M Olivier, N Cermakian - Iscience, 2024 - cell.com
Malaria is a disease caused by infection with parasite Plasmodium spp. We studied the
circadian regulation of host responses to the parasite, in a mouse model of cerebral malaria …

[HTML][HTML] 恶性疟原虫ApiAP2 蛋白质家族研究进展

郑雨昕, 张义伟, 姜宁 - 畜牧兽医学报, 2022 - html.rhhz.net
疟疾是由顶复门寄生虫——疟原虫引起的一种人畜共患病. 疟原虫不仅可以感染人,
还能够感染家禽, 鼠, 食蟹猴等多种动物, 其中, 鸡疟原虫病, 鼠疟原虫病对畜牧业影响较大 …