Computational biology and artificial intelligence in mRNA vaccine design for cancer immunotherapy

S Imani, X Li, K Chen, M Maghsoudloo… - Frontiers in Cellular …, 2025 - frontiersin.org
Messenger RNA (mRNA) vaccines offer an adaptable and scalable platform for cancer
immunotherapy, requiring optimal design to elicit a robust and targeted immune response …

The role of water molecules in CT-DNA interactions: Implications for drug design

S Kumari - Journal of Molecular Liquids, 2024 - Elsevier
In drug design, concentrating on DNA has emerged as a promising method for fighting
various illnesses, including most cancers and genetic disorders. The interaction among …

[HTML][HTML] Development of tetracycline analogues with increased aqueous stability for the treatment of mycobacterial infections

J Liu, GA Phelps, CM Dunn, PA Murphy, LA Wilt… - Tuberculosis, 2025 - Elsevier
Tetracycline analogs from the minocycline family have recently shown promise for the
treatment of non-tuberculous mycobacterial infections. However, current tetracycline and …

[HTML][HTML] The time revolution in macromolecular crystallography

G Khusainov, J Standfuss, T Weinert - Structural Dynamics, 2024 - pubs.aip.org
Macromolecular crystallography has historically provided the atomic structures of proteins
fundamental to cellular functions. However, the advent of cryo-electron microscopy for …

Elucidating the binding specificity of interactive compounds targeting ATP-binding cassette subfamily G member 2 (ABCG2)

P Kumar, I Kumari, R Prasad, S Ray, A Banerjee… - Molecular Diversity, 2025 - Springer
The ATP-binding cassette transporter superfamily plays a pivotal role in cellular
detoxification and drug efflux. ATP-binding cassette subfamily G member 2 (ABCG2) …

The time revolution in macromolecular crystallography

K Georgii, S Joerg, T Weinert - Structural Dynamics, 2024 - search.proquest.com
Macromolecular crystallography has historically provided the atomic structures of proteins
fundamental to cellular functions. However, the advent of cryo-electron microscopy for …