RNA modifications in cancer
Q Tang, L Li, Y Wang, P Wu, X Hou, J Ouyang… - British Journal of …, 2023 - nature.com
Currently, more than 170 modifications have been identified on RNA. Among these RNA
modifications, various methylations account for two-thirds of total cases and exist on almost …
modifications, various methylations account for two-thirds of total cases and exist on almost …
[HTML][HTML] The role of RNA m5C modification in cancer metastasis
Q Zhang, F Liu, W Chen, H Miao, H Liang… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Epigenetic modification plays a crucial regulatory role in the biological processes of
eukaryotic cells. The recent characterization of DNA and RNA methylation is still ongoing …
eukaryotic cells. The recent characterization of DNA and RNA methylation is still ongoing …
DirectRMDB: a database of post-transcriptional RNA modifications unveiled from direct RNA sequencing technology
With advanced technologies to map RNA modifications, our understanding of them has
been revolutionized, and they are seen to be far more widespread and important than …
been revolutionized, and they are seen to be far more widespread and important than …
RM2Target: a comprehensive database for targets of writers, erasers and readers of RNA modifications
X Bao, Y Zhang, H Li, Y Teng, L Ma… - Nucleic Acids …, 2023 - academic.oup.com
RNA modification is a dynamic and reversible process regulated by a series of writers,
erasers and readers (WERs). Abnormal changes of WERs will disrupt the RNA modification …
erasers and readers (WERs). Abnormal changes of WERs will disrupt the RNA modification …
The 2022 Nucleic Acids Research database issue and the online molecular biology database collection
DJ Rigden, XM Fernández - Nucleic acids research, 2022 - academic.oup.com
Abstract The 2022 Nucleic Acids Research Database Issue contains 185 papers, including
87 papers reporting on new databases and 85 updates from resources previously published …
87 papers reporting on new databases and 85 updates from resources previously published …
m6A-Atlas v2.0: updated resources for unraveling the N6-methyladenosine (m6A) epitranscriptome among multiple species
Abstract N 6-Methyladenosine (m6A) is one of the most abundant internal chemical
modifications on eukaryote mRNA and is involved in numerous essential molecular …
modifications on eukaryote mRNA and is involved in numerous essential molecular …
m5C-Atlas: a comprehensive database for decoding and annotating the 5-methylcytosine (m5C) epitranscriptome
Methylcytosine (m5C) is one of the most prevalent covalent modifications on RNA. It is
known to regulate a broad variety of RNA functions, including nuclear export, RNA stability …
known to regulate a broad variety of RNA functions, including nuclear export, RNA stability …
[HTML][HTML] m7GHub V2.0: an updated database for decoding the N7-methylguanosine (m7G) epitranscriptome
With recent progress in mapping N7-methylguanosine (m7G) RNA methylation sites, tens of
thousands of experimentally validated m7G sites have been discovered in various species …
thousands of experimentally validated m7G sites have been discovered in various species …
[HTML][HTML] CircRHBDD1 augments metabolic rewiring and restricts immunotherapy efficacy via m6A modification in hepatocellular carcinoma
J Cai, Z Chen, Y Zhang, J Wang, Z Zhang, J Wu… - Molecular Therapy …, 2022 - cell.com
Circular RNAs are a class of highly conserved RNAs with stable covalently closed circular
structures. Metabolic reprogramming of cancer cells reshapes the tumor microenvironment …
structures. Metabolic reprogramming of cancer cells reshapes the tumor microenvironment …
RMDisease V2. 0: an updated database of genetic variants that affect RNA modifications with disease and trait implication
Recent advances in epitranscriptomics have unveiled functional associations between RNA
modifications (RMs) and multiple human diseases, but distinguishing the functional or …
modifications (RMs) and multiple human diseases, but distinguishing the functional or …