Association between autism spectrum disorders and cardiometabolic diseases: A systematic review and meta-analysis

CS Dhanasekara, D Ancona, L Cortes, A Hu… - JAMA …, 2023 - jamanetwork.com
Importance Although the increased risk of obesity among individuals with autism has been
well established, evidence on the association between autism, cardiometabolic disorders …

Interactions between the lipidome and genetic and environmental factors in autism

CX Yap, AK Henders, GA Alvares, C Giles, K Huynh… - Nature Medicine, 2023 - nature.com
Autism omics research has historically been reductionist and diagnosis centric, with little
attention paid to common co-occurring conditions (for example, sleep and feeding disorders) …

[HTML][HTML] Fetal and neonatal cholesterol metabolism

LA Woollett, JE Heubi - 2016 - europepmc.org
Cholesterol is critical during the development of embryos, fetuses and neonates to support
their growth and development. Cholesterol is a structural component of membranes in every …

Cord blood lipid correlation network profiles are associated with subsequent attention-deficit/hyperactivity disorder and autism spectrum disorder symptoms at 2 years …

K Vacy, S Thomson, A Moore, A Eisner, S Tanner… - …, 2024 - thelancet.com
Background Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder
(ASD) are neurodevelopmental conditions with early life origins. Alterations in blood lipids …

Differentiated approach to pharmacotherapy of autism spectrum disorders: Biochemical aspects

IS Boksha, TA Prokhorova, EB Tereshkina… - Biochemistry …, 2023 - Springer
Abstract Autism Spectrum Disorders (ASD) are highly heterogeneous neurodevelopmental
disorders caused by a complex interaction of numerous genetic and environmental factors …

Unveiling the crucial neuronal role of the proteasomal ATPase subunit gene PSMC5 in neurodevelopmental proteasomopathies

S Küry, JE Stanton, G van Woerden, TC Hsieh… - medRxiv, 2024 - medrxiv.org
Neurodevelopmental proteasomopathies represent a distinctive category of
neurodevelopmental disorders (NDD) characterized by genetic variations within the 26S …

Genetic Determinants of Atherogenic Indexes

T Texis, S Rivera-Mancía, E Colín-Ramírez… - Genes, 2023 - mdpi.com
Atherogenesis and dyslipidemia increase the risk of cardiovascular disease, which is the
leading cause of death in developed countries. While blood lipid levels have been studied …

Screening autism-associated environmental factors in differentiating human neural progenitors with fractional factorial design-based transcriptomics

A Arora, M Becker, C Marques, M Oksanen, D Li… - Scientific Reports, 2023 - nature.com
Research continues to identify genetic variation, environmental exposures, and their
mixtures underlying different diseases and conditions. There is a need for screening …

ARGENT: Multi-task learning model for predicting autism-related genes and drug targets using heterogeneous graph convolutional network

X Miao, W Yu - Future Generation Computer Systems, 2024 - Elsevier
Abstract Autism Spectrum Disorder (ASD) is a multifactorial-driven neurodevelopmental
disorder, the pathophysiological mechanisms of which remain largely elusive, significantly …

Is cholesterol both the lock and key to abnormal transmembrane signals in Autism Spectrum Disorder?

C Lingwood - Lipids in Health and Disease, 2024 - Springer
Disturbances in cholesterol homeostasis have been associated with ASD. Lipid rafts are
central in many transmembrane signaling pathways (including mTOR) and changes in raft …