Autism omics research has historically been reductionist and diagnosis centric, with little attention paid to common co-occurring conditions (for example, sleep and feeding disorders) …
Cholesterol is critical during the development of embryos, fetuses and neonates to support their growth and development. Cholesterol is a structural component of membranes in every …
K Vacy, S Thomson, A Moore, A Eisner, S Tanner… - …, 2024 - thelancet.com
Background Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are neurodevelopmental conditions with early life origins. Alterations in blood lipids …
IS Boksha, TA Prokhorova, EB Tereshkina… - Biochemistry …, 2023 - Springer
Abstract Autism Spectrum Disorders (ASD) are highly heterogeneous neurodevelopmental disorders caused by a complex interaction of numerous genetic and environmental factors …
Neurodevelopmental proteasomopathies represent a distinctive category of neurodevelopmental disorders (NDD) characterized by genetic variations within the 26S …
Atherogenesis and dyslipidemia increase the risk of cardiovascular disease, which is the leading cause of death in developed countries. While blood lipid levels have been studied …
A Arora, M Becker, C Marques, M Oksanen, D Li… - Scientific Reports, 2023 - nature.com
Research continues to identify genetic variation, environmental exposures, and their mixtures underlying different diseases and conditions. There is a need for screening …
X Miao, W Yu - Future Generation Computer Systems, 2024 - Elsevier
Abstract Autism Spectrum Disorder (ASD) is a multifactorial-driven neurodevelopmental disorder, the pathophysiological mechanisms of which remain largely elusive, significantly …
C Lingwood - Lipids in Health and Disease, 2024 - Springer
Disturbances in cholesterol homeostasis have been associated with ASD. Lipid rafts are central in many transmembrane signaling pathways (including mTOR) and changes in raft …