Genes | Free Full-Text | Two-Component Systems of S. aureus: Signaling and Sensing Mechanisms
Next Article in Journal Genome-Wide Identification, Primary Functional Characterization of the …

The widespread bacterial second messenger c-di-GMP is responsible for regulating many
important physiological functions such as biofilm formation, motility, cell differentiation, and …

The development of new antibiotics continues to pose challenges, particularly considering
the growing threat of multidrug-resistant Staphylococcus aureus. Structurally diverse natural …

Background: Staphylococcus aureus is a major bacterial pathogen capable of causing a
range of infections in humans from gastrointestinal disease, skin and soft tissue infections, to …

WalKR (YycFG) is the only essential two-component regulator in the human pathogen
Staphylococcus aureus. WalKR regulates peptidoglycan synthesis, but this function alone …

Staphylococcus aureus is a facultative pathogen that can encode numerous antibiotic
resistance and immune evasion genes and can cause severe infections. Reduced …

Strains of Ralstonia solanacearum species complex (RSSC) cause “bacterial wilt” on a wide
range of plant species and thus lead to marked economic losses in agriculture. Quorum …

As the issues surrounding antibiotic‑resistant strains of Staphylococcus aureus (S. aureus)
are becoming increasingly serious concerns, it is imperative to investigate new therapeutic …

Abstract The WalK/WalR two-component system (TCS), originally identified in Bacillus
subtilis, is very highly conserved in gram-positive bacteria, including several important …

The glycopeptide antibiotic vancomycin has been widely used to treat infections of Gram-
positive bacteria including Clostridium difficile and methicillin-resistant Staphylococcus …