Future prospects in the tissue engineering of heart valves: A focus on the role of stem cells

BJ Albert, JT Butcher - Expert opinion on biological therapy, 2023 - Taylor & Francis
Introduction Heart valve disease is a growing burden on the healthcare system. Current
solutions are insufficient for young patients and do not offer relief from reintervention. Tissue …

Stem cell‐derived extracellular vesicles reduce the expression of molecules involved in cardiac hypertrophy—In a model of human-induced pluripotent stem cell …

A Constantin, IK Comarița, N Alexandru… - Frontiers in …, 2022 - frontiersin.org
Cardiac pathological hypertrophy is the major risk factor that usually progresses to heart
failure. We hypothesized that extracellular vesicles (EVs), known to act as important …

The path to a hemocompatible cardiovascular implant: Advances and challenges of current endothelialization strategies

V Exarchos, E Zacharova, S Neuber… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular (CV) implants are still associated with thrombogenicity due to insufficient
hemocompatibility. Endothelialization of their luminal surface is a promising strategy to …

Tissue engineered pulmonary valve repair material for use in an in-vitro preclinical model of pediatric valve augmentation

M Lecce - 2022 - search.proquest.com
Pediatric pulmonary valves are commonly repaired by monocusp augmentation, but current
repair materials cannot grow, necessitating reintervention. Heart valve tissue engineering …

Evolution of Device Therapies for Cardiovascular Surgical Care in Children

A Phillips, H Najm - Advances in Cardiovascular Technology, 2022 - Elsevier
Device therapies are critical for the success of cardiovascular therapies in children. The
history of heart surgery began with advancements in the treatment of congenital heart …

[引用][C] Alina Constantin1, Ioana Karla Comariţa1, Nicoleta Alexandru1, Alexandru Filippi1, 2, Florina Bojin3, 4, Mihaela Gherghiceanu2, 5, Alexandra Vîlcu1, Miruna …

A Constantin, IK Comariţa - 2022 - europepmc.org
Hypertension is a major risk factor that contributes along with obesity, genetic predisposition
and environmental factors to severity of cardiovascular disease, a leading cause of mortality …