Thiazoles, their benzofused systems, and thiazolidinone derivatives are widely recognized
as nuclei of great value for obtaining molecules with various biological activities, including …

Antimicrobial resistance is one of the greatest challenges facing the world today. In the
United States alone, it is responsible for the death of more than 20,000 people each year …

Novel sixty three quinoline-3-carbonitrile derivatives were synthesized starting from 6-
substituted-2-hydrazinyl quinoline-3-carbonitrile. The synthesized compounds were …

Thiazole, a five-membered heterocyclic compound constitutes the skeleton of various
commercially marketed drug candidates and the heart-core in a diverse range of entities of …

Abstract A solid-state photoluminescent 4-(Dimethylamino)-2ʹ-hydroxychalcone (Chalcone)
compound was designed and synthesized using the Claisen–Schmidt condensation …

A series of novel thienopyridines and pyridothienoquinolines (3a, b–14) was synthesized,
starting with 2-thioxo-1, 2-dihydropyridine-3-carbonitriles 1a and 1b. All compounds were …

Abstract A series of new 1, 2, 4-triazole and 1, 3, 4-oxadiazole derivatives was obtained via
several steps sequential reactions of phenyl piperazine. Then, these compounds were …

Four new Schiff-bases have been synthesized from the 1: 2 M condensation of 4, 5, 6, 7-
tetrahydrobenzothiazole-2, 6-diamine with 2-hydroxybenzaldehyde (SL 1), 5-Bromo-2 …

The inhibition of pathogenic bacteria at the replication stage is important to halt their further
reproduction and spread. The replication enzymes include the DNA gyrase and …

New antibacterials that modulate less explored targets are needed to fight the emerging
bacterial resistance. DNA gyrase and topoisomerase IV are attractive targets in this search …