[HTML][HTML] Decoding Non-coding Variants: Recent Approaches to Studying Their Role in Gene Regulation and Human Diseases
EG Peña-Martínez… - Frontiers in bioscience …, 2024 - ncbi.nlm.nih.gov
Genome-wide association studies (GWAS) have mapped over 90% of disease-and
quantitative-trait-associated variants within the non-coding genome. Non-coding regulatory …
quantitative-trait-associated variants within the non-coding genome. Non-coding regulatory …
Cardiovascular Disease-Associated Non-Coding Variants Disrupt GATA4-DNA Binding and Regulatory Functions
EG Peña-Martínez, JL Messon-Bird… - bioRxiv, 2024 - biorxiv.org
Genome-wide association studies have mapped over 90% of cardiovascular disease (CVD)-
associated variants within the non-coding genome. Non-coding variants in regulatory …
associated variants within the non-coding genome. Non-coding variants in regulatory …
Identification of key genes and signaling pathway in the pathogenesis of Huntington's disease via bioinformatics and next generation sequencing data analysis
BM Vastrad, CM Vastrad - bioRxiv, 2024 - biorxiv.org
Huntington's disease (HD) is the primary cause of progressive motor deficits, psychiatric
symptoms, and cognitive impairment. The exact molecular mechanisms of HD pathogenesis …
symptoms, and cognitive impairment. The exact molecular mechanisms of HD pathogenesis …