TM Leibiger, LA Remmler, EA Green, KH Lee - Molecular Therapy Methods …, 2024 - cell.com
Faster and more accurate analytical methods are needed to support the advancement of recombinant adeno-associated virus (rAAV) production systems. Recently, biolayer …
J Yan, Z Li, Y Shu, H Chen, T Wang, X Li, Y Zhang… - Gene, 2025 - Elsevier
The field of gene therapy using Adeno-associated viral (AAV) vector delivery is rapidly advancing in the biotherapeutics industry. Despite its successes, AAV manufacturing …
J Tworig, F Grafton, K Fisher, M Hörer, CA Reid… - … Therapy Methods & …, 2024 - cell.com
Recombinant adeno-associated virus (rAAV) is a widely used viral vector for gene therapy. However, these vectors have limited availability due to manufacturing challenges with …
X Ye, Y Hu, H Qiu, N Li - Protein Science, 2024 - Wiley Online Library
Abstract Adeno‐associated virus (AAV), a widely used gene therapy vector, is a small, nonenveloped virus that contains a single‐stranded DNA genome with a maximum length of …
J Tworig, F Grafton, M Horer, CA Reid, MA Mandegar - bioRxiv, 2024 - biorxiv.org
Recombinant adeno-associated virus (rAAV) is a widely used viral vector for gene therapy. Despite its clinical efficacy, the manufacturing of rAAV faces challenges in productivity and …
The production of recombinant adeno-associated virus (rAAV) for gene therapy via triple transfection is a highly intricate process involving many cellular interactions. Each of the …
Recombinant adeno associated virus (rAAV) vectors have become popular delivery vehicles for in vivo gene therapies, but demand for rAAVs continues to outpace supply due to low …
Lentiviral vectors are highly efficient gene delivery vehicles used extensively in the rapidly growing field of cell and gene therapy to treat a wide range of diseases. Demand for …