Atherosclerotic cardiovascular disease in South Asians in the United States: epidemiology, risk factors, and treatments: a scientific statement from the American Heart …
South Asians (from Bangladesh, Bhutan, India, the Maldives, Nepal, Pakistan, and Sri
Lanka) make up one quarter of the world's population and are one of the fastest-growing …
Lanka) make up one quarter of the world's population and are one of the fastest-growing …
[HTML][HTML] Meta-regression analysis of the effects of dietary cholesterol intake on LDL and HDL cholesterol
MJ Vincent, B Allen, OM Palacios, LT Haber… - The American journal of …, 2019 - Elsevier
Background Elevated low-density lipoprotein (LDL) cholesterol is a major risk factor for
cardiovascular disease. Dietary guidance recommends reducing saturated fatty acid, trans …
cardiovascular disease. Dietary guidance recommends reducing saturated fatty acid, trans …
Extending the MR‐Egger method for multivariable Mendelian randomization to correct for both measured and unmeasured pleiotropy
Methods have been developed for Mendelian randomization that can obtain consistent
causal estimates while relaxing the instrumental variable assumptions. These include …
causal estimates while relaxing the instrumental variable assumptions. These include …
Powerful three-sample genome-wide design and robust statistical inference in summary-data Mendelian randomization
Abstract Background Summary-data Mendelian randomization (MR) has become a popular
research design to estimate the causal effect of risk exposures. With the sample size of …
research design to estimate the causal effect of risk exposures. With the sample size of …
[HTML][HTML] ω-6 polyunsaturated fatty acids and cardiometabolic health: current evidence, controversies, and research gaps
KC Maki, F Eren, ME Cassens, MR Dicklin… - Advances in …, 2018 - Elsevier
Abstract The 2015 Dietary Guidelines for Americans recommend limiting the intake of
saturated fatty acids (SFAs) to< 10% of energy/d and replacing dietary SFAs with …
saturated fatty acids (SFAs) to< 10% of energy/d and replacing dietary SFAs with …
Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease
Background Plasminogen activator inhibitor type 1 (PAI‐1) plays an essential role in the
fibrinolysis system and thrombosis. Population studies have reported that blood PAI‐1 levels …
fibrinolysis system and thrombosis. Population studies have reported that blood PAI‐1 levels …
Cholesterol efflux capacity and its association with adverse cardiovascular events: a systematic review and meta-analysis
Background: Serum high-density lipoprotein cholesterol (HDL-C) levels are inversely
associated with cardiovascular disease events. Yet, emerging evidence suggests that it is …
associated with cardiovascular disease events. Yet, emerging evidence suggests that it is …
Genetics: implications for prevention and management of coronary artery disease
TL Assimes, R Roberts - Journal of the American College of cardiology, 2016 - jacc.org
An exciting new era has dawned for the prevention and management of coronary artery
disease (CAD) utilizing genetic risk variants. The recent identification of over 60 …
disease (CAD) utilizing genetic risk variants. The recent identification of over 60 …
[HTML][HTML] Circulating ceramides as biomarkers of cardiovascular disease: Evidence from phenotypic and genomic studies
KA McGurk, BD Keavney, A Nicolaou - Atherosclerosis, 2021 - Elsevier
There is a need for new biomarkers of atherosclerotic cardiovascular disease (ACVD), the
main cause of death globally. Ceramides, a class of potent bioactive lipid mediators, have …
main cause of death globally. Ceramides, a class of potent bioactive lipid mediators, have …
Advances in lipidomics
HF Avela, H Siren - Clinica Chimica Acta, 2020 - Elsevier
The present article examines recently published literature on lipids, mainly focusing on
research involving glycero-, glycerophospho-and sphingo-lipids. The primary aim is …
research involving glycero-, glycerophospho-and sphingo-lipids. The primary aim is …