Bronchiectasis refers to abnormal dilatation of the bronchi. Airway dilatation can lead to
failure of mucus clearance and increased risk of infection. Pathophysiological mechanisms …

The diagnosis, investigation and particularly management of bronchiectasis has been
largely empirical and the subject of relatively few controlled clinical trials. There are no clear …

There is increasing awareness of bronchiectasis in children and adolescents, a chronic
pulmonary disorder associated with poor quality of life for the child/adolescent and their …

Background Indigenous children in high-income countries have a heavy burden of
bronchiectasis unrelated to cystic fibrosis. We aimed to establish whether long-term …

Bronchiectasis is described classically as a chronic pulmonary disorder characterized by a
persistent productive cough and irreversible dilatation of one or more bronchi. However, in …

Background: Persistent bacterial bronchitis (PBB) seems to be under-recognised and often
misdiagnosed as asthma. In the absence of published data relating to the management and …

In the modern era, the global burden of childhood chronic suppurative lung disease (CSLD)
remains poorly captured by the literature. What is clear, however, is that CSLD is essentially …

Objective Indigenous children in developed countries are at increased risk of chronic
suppurative lung disease (CSLD), including bronchiectasis. We evaluated …

OBJECTIVE: To test the hypothesis that bacterial density, strain diversity, and concordance
of pathogens between upper and lower airways are higher in children with bronchiectasis …

In an era when Haemophilus influenzae type b (Hib) conjugate vaccine is widely used, the
incidence of Hib as a cause of community-acquired pneumonia (CAP) has dramatcally …