FLASH radiotherapy and the use of radiation dosimeters

S Siddique, HE Ruda, JCL Chow - Cancers, 2023 - mdpi.com
Simple Summary FLASH radiotherapy (RT) delivering ultra-high dose rate radiation can
reduce normal tissue toxicity while effectively treating tumors. However, implementing …

[HTML][HTML] Framework for quality assurance of ultrahigh dose rate clinical trials investigating FLASH effects and current technology gaps

W Zou, R Zhang, E Schüler, PA Taylor… - International Journal of …, 2023 - Elsevier
Abstract FLASH radiation therapy (FLASH-RT), delivered with ultrahigh dose rate (UHDR),
may allow patients to be treated with less normal tissue toxicity for a given tumor dose …

A diamond detector based dosimetric system for instantaneous dose rate measurements in FLASH electron beams

M Marinelli, F di Martino, D Del Sarto… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. A reliable determination of the instantaneous dose rate (I-DR) delivered in FLASH
radiotherapy treatments is believed to be crucial to assess the so-called FLASH effect in …

[HTML][HTML] Charge collection efficiency, underlying recombination mechanisms, and the role of electrode distance of vented ionization chambers under ultra-high dose …

R Kranzer, A Schüller, FG Rodríguez, J Weidner… - Physica Medica, 2022 - Elsevier
Purpose Investigating and understanding of the underlying mechanisms affecting the charge
collection efficiency (CCE) of vented ionization chambers under ultra-high dose rate pulsed …

Passive SOBP generation from a static proton pencil beam using 3D-printed range modulators for FLASH experiments

F Horst, E Beyreuther, E Bodenstein, S Gantz… - Frontiers in …, 2023 - frontiersin.org
The University Proton Therapy facility in Dresden (UPTD), Germany, is equipped with an
experimental room with a beamline providing a static pencil beam. High proton beam …

Thermal neutron detection and track recognition method in reference and out-of-field radiotherapy FLASH electron fields using Timepix3 detectors

C Oancea, J Solc, A Bourgouin, C Granja… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. This work presents a method for enhanced detection, imaging, and measurement
of the thermal neutron flux. Approach. Measurements were performed in a water tank, while …

Simulation study of protoacoustics as a real‐time in‐line dosimetry tool for FLASH proton therapy

K Kim, PK Pandey, G Gonzalez, Y Chen… - Medical …, 2024 - Wiley Online Library
Background Applying ultra‐high dose rates to radiation therapy, otherwise known as
FLASH, has been shown to be just as effective while sparing more normal tissue compared …

[HTML][HTML] Enabling ultra-high dose rate electron beams at a clinical linear accelerator for isocentric treatments

R Dal Bello, J von der Grün, S Fabiano, T Rudolf… - Radiotherapy and …, 2023 - Elsevier
Abstract Background and Purpose Radiotherapy delivery with ultra-high dose rates (UHDR)
has consistently produced normal tissue sparing while maintaining efficacy for tumour …

Absorbed-dose-to-water measurement using alanine in ultra-high-pulse-dose-rate electron beams

A Bourgouin, T Hackel, M Marinelli… - Physics in Medicine …, 2022 - iopscience.iop.org
Objective. The aim of the presented study is to evaluate the dose response of the PTB's
secondary standard system, which is based on alanine and electron spin resonance (ESR) …

Applications of carbon-based diamond detectors: A critical review

UF Ahmad, YS Wudil, A Imam, NF Isa… - Materials Today …, 2023 - Elsevier
Diamond has emerged as the desirable semiconducting material in radiation detectors
owing to its extremely wide band gap that favors certain outstanding properties. Such …