Cancer stem cells (CSCs) show a self-renewal capacity and differentiation potential that
contribute to tumor progression and therapy resistance. However, the underlying processes …

Oncogenic activation of the phosphatidylinositol-3-kinase (PI3K), protein kinase B
(PKB/AKT), and mammalian target of rapamycin (mTOR) pathway is a frequent event in …

Prostate cancer (PCa) affects millions of men globally. Due to advances in understanding
genomic landscapes and biological functions, the treatment of PCa continues to improve …

Gastrointestinal enterochromaffin cells regulate bone and gut homeostasis via serotonin (5-
hydroxytryptamine [5-HT]) production. A recent report suggested that gut microbes regulate …

Prostate cancer (PCa) is a prevalent malignancy that occurs primarily in old males. Prostate
tumors in different patients manifest significant inter-patient heterogeneity with respect to …

Prostate cancer is the second most common malignancy in men and androgen deprivation
therapy is the first‐line therapy. However, most cases will eventually develop castration …

Prostate cancer is the most frequent nonskin cancer and second most common cause of
cancer-related deaths in man. Prostate cancer is a clinically heterogeneous disease with …

Background Metastatic castration-resistant prostate cancer (mCRPC) is the lethal form of the
disease. Several recent studies have identified genomic alterations in mCRPC, but the …

Temozolomide (TMZ) resistance is a major cause of recurrence and poor prognosis in
glioblastoma (GBM). Recently, increasing evidences suggested that long noncoding RNAs …

Prostate cancer is the second most common cancer diagnosed in men and the fifth-leading
cause of cancer death in men worldwide. Like any solid tumor, the hypoxic …