The mood stabilizers lithium and valproic acid (VPA) are traditionally used to treat bipolar
disorder (BD), a severe mental illness arising from complex interactions between genes and …

Fragile X syndrome (FXS) is the most frequent form of inherited intellectual disability and is
also linked to other neurologic and psychiatric disorders. FXS is caused by a triplet …

The FMR1 mutations can cause a variety of disabilities, including cognitive deficits, attention-
deficit/hyperactivity disorder, autism, and other socioemotional problems, in individuals with …

Abstract Objective Fragile X syndrome (FXS) has been the neurodevelopmental disorder
with the most active translation of preclinical breakthroughs into clinical trials. This process …

Background: Attention-deficit/hyperactivity disorder (ADHD) is one of the most prevalent
psychiatric conditions in childhood. Dietary changes have been suggested as a way of …

Objective: Progress in basic neuroscience has led to identification of molecular targets for
treatment in fragile X syndrome (FXS) and other neurodevelopmental disorders; however …

Background: Early detection and diagnosis are very important for autism. Current diagnosis
of autism relies mainly on some observational questionnaires and interview tools that may …

Fragile X syndrome (FXS) is the leading monogenic cause of intellectual disability and
autism. The FMR1 gene contains a CGG repeat present in the 5′‐untranslated region …

L-carnitine plays an important role in the functioning of the central nervous system, and
especially in the mitochondrial metabolism of fatty acids. Altered carnitine metabolism …

Evidence-based pharmacotherapy options in people with intellectual disability are limited,
and many agents can cause substantial adverse events. For this reason, clinicians should …