With more than 4 million intensive care unit (ICU) admissions per year in the United States,
there is increasing recognition of the long-term consequences of ICU care on the physical …

Dexmedetomidine is a potent, highly selective α-2 adrenoceptor agonist, with sedative,
analgesic, anxiolytic, sympatholytic, and opioid-sparing properties. Dexmedetomidine …

Background Dexmedetomidine produces sedation while maintaining a degree of
arousability and may reduce the duration of mechanical ventilation and delirium among …

Delirium is the most common neuropsychiatric syndrome found in the acute care setting,
with a prevalence ranging from 10% in general medicine to 85% in advanced cancer and …

Background Guidelines currently recommend targeting light sedation with dexmedetomidine
or propofol for adults receiving mechanical ventilation. Differences exist between these …

Sepsis is a major cause of death in intensive care units worldwide. The acute phase of
sepsis is often accompanied by sepsis-associated encephalopathy, which is highly …

Objectives: To assess the knowledge and use of the Assessment, prevention, and
management of pain; spontaneous awakening and breathing trials; Choice of analgesia and …

Background Delirium is a common mental disorder, which is distressing and has serious
adverse outcomes in hospitalised patients. Prevention of delirium is desirable from the …

Pneumonia is a type of acute lower respiratory infection that is common and severe. The
outcome of lower respiratory infection is determined by the degrees to which immunity is …

Dexmedetomidine (Dexdor®) is a highly selective α 2-adrenoceptor agonist. It has sedative,
analgesic and opioid-sparing effects and is suitable for short-and longer-term sedation in an …