Over a century of scientific inquiry since the discovery of v-SRC but still no final judgement
on SRC function. However, a significant body of work has defined Src family kinases as key …

Abstract The Src family kinases (SFKs) are cytoplasmic non-receptor tyrosine kinases
involved in multiple signalling pathways. In the central nervous system (CNS), SFKs are key …

Excitatory neurotransmission meditated by glutamate receptors including N-methyl-D-
aspartate receptors (NMDARs) is pivotal to brain development and function. NMDARs are …

In addition to its role as a neuronal energy substrate and signaling molecule involved in
synaptic plasticity and memory consolidation, recent evidence shows that lactate produces …

NMDA receptor (NMDAR)-mediated calcium influx triggers the induction and initial
expression of long-term potentiation (LTP). Here we report that in male rodents, ion flux …

Alternative splicing of Grin1 exon 5 regulates induction of long-term potentiation (LTP) at
Schaffer collateral-CA1 synapses: LTP in mice lacking the GluN1 exon 5-encoded N1 …

Src, the prototype of Src family kinases (SFKs), is a modular protein consisting of SH4 (SH4)
and unique (UD) domains in an N-terminal intrinsically disordered region (IDR), and SH3 …

Src is a non-receptor tyrosine kinase participating in a range of neuronal processes,
including synaptic plasticity. We have recently shown that the amounts of total Src and its …

Mutations in N-methyl-d-aspartate receptors (NMDAR) subunits have been implicated in a
growing number of human neurodevelopmental disorders. Previously, a de novo mutation in …

Men generally outperform women on encoding spatial components of episodic memory
whereas the reverse holds for semantic elements. Here we show that female mice …