Benchtop NMR spectroscopy has known a major growth over the last decade, thanks to the
design of permanent, compact magnets in the 1–2 T range, that provide remarkable …

Despite great successes in oncology, patient outcomes are often still discouraging, and
hence the diagnostic imaging paradigm is increasingly shifting toward functional imaging of …

The unique properties of the entangled, antisymmetric nuclear spin state of dihydrogen,
parahydrogen (pH2), has intrigued physicists, chemists, and other scientists for almost a …

We present a versatile method for the preparation of hyperpolarized [1-13C] fumarate as a
contrast agent for preclinical in vivo MRI, using parahydrogen-induced polarization (PHIP) …

Parahydrogen-induced polarisation (PHIP) is a nuclear spin hyperpolarisation technique
employed to enhance NMR signals for a wide range of molecules. This is achieved by …

We report on a robust and low-cost parahydrogen generator design employing liquid
nitrogen as a coolant. The core of the generator consists of catalyst-filled spiral copper …

Because of the extensive chemical, physical, and biomedical applications of parahydrogen,
the need exists for the development of highly enriched parahydrogen in a robust and …

We demonstrate that heterogeneous/biphasic chemical reactions can be monitored with
high spectroscopic resolution using zero‐field nuclear magnetic resonance spectroscopy …

Parahydrogen-induced polarization of 13C nuclei by side-arm hydrogenation (PHIP-SAH)
for [1-13C] acetate and [1-13C] pyruvate esters with application of PH-INEPT-type pulse …

Hyperpolarized contrast agents (HyCAs) have enabled unprecedented magnetic resonance
imaging (MRI) of metabolism and pH in vivo. Producing HyCAs with currently available …