RNA is now known to possess various structural, regulatory and enzymatic functions for
survival of cellular organisms. Functional RNA structures are generally created by three …

Molecular dynamics simulations are performed for mixtures of ethylene glycol (EG) and
water with EG mass fraction of C i= 0%, 20%, 40%, 60%, 80%, 100%. The extensively …

A large amount of experimental evidence is available on the effect of magnesium ions on the
structure and stability of DNA double helix. Less is known, however, on how these ions affect …

RNA contains different secondary structural motifs like pseudo-helices, hairpin loops,
internal loops, etc. in addition to anti-parallel double helices and random coils. The …

The three-dimensional structure of DNA contains various sequence-dependent structural
information, which control many cellular processes in life, such as replication, transcription …

Noncanonical basepairs have gained importance over the past few years because of their
various functions in RNA biochemistry. These basepairs appear quite frequently in different …

DNA is an essential target for the treatment of various pathologies, especially cancer. Hence
targeting DNA double helix for alteration of its function has been attempted by several ways …

Understanding dinucleotide sequence directed structures of nuleic acids and their variability
from experimental observation remained ineffective due to unavailability of statistically …

The present article aims to investigate the ability of a DNA origami nanocarrier to
successfully capture a cargo using molecular dynamics (MD) simulation. In addition, the …

Internal loops within RNA duplex regions are formed by single or tandem basepairing
mismatches with flanking canonical Watson–Crick basepairs on both sides. They are the …