Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment

RA McCutcheon, RSE Keefe, PK McGuire - Molecular psychiatry, 2023 - nature.com
Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this …

Schizophrenia—an overview

RA McCutcheon, TR Marques, OD Howes - JAMA psychiatry, 2020 - jamanetwork.com
Importance Schizophrenia is a common, severe mental illness that most clinicians will
encounter regularly during their practice. This report provides an overview of the clinical …

[HTML][HTML] Functional brain networks are dominated by stable group and individual factors, not cognitive or daily variation

C Gratton, TO Laumann, AN Nielsen, DJ Greene… - Neuron, 2018 - cell.com
The organization of human brain networks can be measured by capturing correlated brain
activity with fMRI. There is considerable interest in understanding how brain networks vary …

[HTML][HTML] Using deep learning to investigate the neuroimaging correlates of psychiatric and neurological disorders: Methods and applications

S Vieira, WHL Pinaya, A Mechelli - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Deep learning (DL) is a family of machine learning methods that has gained considerable
attention in the scientific community, breaking benchmark records in areas such as speech …

Common dysfunction of large-scale neurocognitive networks across psychiatric disorders

Z Sha, TD Wager, A Mechelli, Y He - Biological psychiatry, 2019 - Elsevier
Background Cognitive dysfunction is one of the most prominent characteristics of psychiatric
disorders. Currently, the neural correlates of cognitive dysfunction across psychiatric …

Revisiting the functional anatomy of the human brain: toward a meta-networking theory of cerebral functions

G Herbet, H Duffau - Physiological Reviews, 2020 - journals.physiology.org
For more than one century, brain processing was mainly thought in a localizationist
framework, in which one given function was underpinned by a discrete, isolated cortical …

Machine learning in resting-state fMRI analysis

M Khosla, K Jamison, GH Ngo, A Kuceyeski… - Magnetic resonance …, 2019 - Elsevier
Abstract Machine learning techniques have gained prominence for the analysis of resting-
state functional Magnetic Resonance Imaging (rs-fMRI) data. Here, we present an overview …

Multi-site diagnostic classification of schizophrenia using discriminant deep learning with functional connectivity MRI

LL Zeng, H Wang, P Hu, B Yang, W Pu, H Shen… - …, 2018 - thelancet.com
Background A lack of a sufficiently large sample at single sites causes poor generalizability
in automatic diagnosis classification of heterogeneous psychiatric disorders such as …

Neural substrates of reward anticipation and outcome in schizophrenia: a meta-analysis of fMRI findings in the monetary incentive delay task

J Zeng, J Yan, H Cao, Y Su, Y Song, Y Luo… - Translational …, 2022 - nature.com
Dysfunction of the mesocorticolimbic dopaminergic reward system is a core feature of
schizophrenia (SZ), yet its precise contributions to different stages of reward processing and …

Discriminating schizophrenia using recurrent neural network applied on time courses of multi-site FMRI data

W Yan, V Calhoun, M Song, Y Cui, H Yan, S Liu… - …, 2019 - thelancet.com
Background Current fMRI-based classification approaches mostly use functional
connectivity or spatial maps as input, instead of exploring the dynamic time courses directly …