Mucormycosis in 2023: An update on pathogenesis and management

A Alqarihi, DP Kontoyiannis, AS Ibrahim - Frontiers in Cellular and …, 2023 - frontiersin.org
Mucormycosis (MCR) is an emerging and frequently lethal fungal infection caused by the
Mucorales family, with Rhizopus, Mucor, and Lichtheimia, accounting for> 90% of all cases …

Mucorales and Mucormycosis: Recent Insights and Future Prospects

G Tahiri, C Lax, JT Cánovas-Márquez, P Carrillo-Marín… - Journal of Fungi, 2023 - mdpi.com
The classification of Mucorales encompasses a collection of basal fungi that have
traditionally demonstrated an aversion to modern genetic manipulation techniques. This …

Molecular mechanisms that govern infection and antifungal resistance in Mucorales

C Lax, FE Nicolás, E Navarro… - … and Molecular Biology …, 2024 - Am Soc Microbiol
SUMMARY The World Health Organization has established a fungal priority pathogens list
that includes species critical or highly important to human health. Among them is the order …

Epidemiology, pathogenesis, clinical characteristics, and treatment of mucormycosis: a review

M Liang, J Xu, Y Luo, J Qu - Annals of Medicine, 2024 - Taylor & Francis
Aim This review aims to summarize the epidemiology, etiology, pathogenesis, clinical
manifestations, and current diagnostic and therapeutic approaches for mucormycosis. The …

[HTML][HTML] Unlocking Fungal Potential: The CRISPR-Cas System as a Strategy for Secondary Metabolite Discovery

K Leal, E Rojas, D Madariaga, MJ Contreras… - Journal of Fungi, 2024 - mdpi.com
Natural products (NPs) are crucial for the development of novel antibiotics, anticancer
agents, and immunosuppressants. To highlight the ability of fungi to produce structurally …

Blood serum stimulates the virulence potential of mucorales through enhancement in mitochondrial oxidative metabolism and rhizoferrin production

JA Patiño-Medina, V Alejandre-Castañeda… - Journal of Fungi, 2023 - mdpi.com
This study analyzed the role of blood serum in enhancing the mitochondrial metabolism and
virulence of Mucorales through rhizoferrin secretion. We observed that the spores of …

The utility of Drosophila melanogaster as a fungal infection model

CD Mpamhanga, I Kounatidis - Frontiers in Immunology, 2024 - frontiersin.org
Invasive fungal diseases have profound effects upon human health and are on increase
globally. The World Health Organization (WHO) in 2022 published the fungal priority list …

Advances in understanding infections caused by the basal fungus Mucor

JT Cánovas-Márquez, C Lax, G Tahiri, E Navarro… - PLoS …, 2023 - journals.plos.org
AU: Pleaseconfirmthatallheadinglevelsarerepre…. Mucormycosis represents a group of
infections with different organ manifestations caused by some species of the fungal order …

Comprehensive Review on the Virulence Factors and Therapeutic Strategies with the Aid of Artificial Intelligence against Mucormycosis

M Tanwar, A Singh, TP Singh, S Sharma… - ACS Infectious …, 2024 - ACS Publications
Mucormycosis, a rare but deadly fungal infection, was an epidemic during the COVID-19
pandemic. The rise in cases (COVID-19-associated mucormycosis, CAM) is attributed to …

Alternative in-vivo models of mucormycosis

J Scheler, U Binder - Frontiers in Cellular and Infection Microbiology, 2024 - frontiersin.org
Mucormycosis is still regarded a rare fungal infection, but the high incidences of COVID-
associated cases in India and other countries have shown its potential threat to large patient …