Simple Summary Personalized neoantigen vaccines are a diverse group of personally
tailored cancer vaccines that strengthen patients´ own immune reaction against cancer …

In this review, we discuss the use of the alkylating agent temozolomide (TMZ) in the
treatment of IDH-mutant gliomas. We describe the challenges associated with TMZ in clinical …

Diffuse lower-grade gliomas (LGG) represent the highly heterogeneous and infiltrative
neoplasms in the central nervous system (CNS). Replication factor C 2 (RFC2) is a subunit …

Purpose To predict chromosome 7 gain and chromosome 10 loss (+ 7/-10) in IDH wild-type
(IDH-wt) histologically low-grade gliomas (LGG) by machine learning models based on MRI …

Simple Summary Low-grade glioma are primary brain tumors mostly with IDH mutations,
usually occurring in young patients, with a clinically good prognosis. Here, we analyzed …

Glioma is the most common malignant tumor of the central nervous system and resistance is
easily developed to chemotherapy drugs during the treatment process, resulting in high …

Objectives: Identify the etiology and epidemiology of the central nervous system neoplasm
oligodendroglioma. Review the presentation and diagnosis of oligodendroglioma. Describe …

Gliomas are the most prevalent primary tumors in the central nervous system. Despite some
breakthroughs in the treatment of glioma in recent years, survival rates remain low. Although …

To elucidate the role of miRNA-27a-3p in inducing Temozolomide (TMZ) resistance in
glioma and the underlying mechanism. Relative levels of miRNA-27a-3p and NF1 in glioma …

In the present study, novel, 1, 3-diaryltriazene-derived triazene compounds were
synthesized and tested. Triazenes are versatile and belong to a group of alkylating agents …