Many organisms have stress response pathways, components of which share homology
with players in complex human disease pathways. Research on stress response in the …

Although many studies have examined quantitative trait variation across many species, only
a small number of genes and thereby molecular mechanisms have been discovered …

Natural products are small molecules naturally produced by multiple sources such as plants,
animals, fungi, bacteria and archaea. They exert both beneficial and detrimental effects by …

The genetic variants underlying complex traits are often elusive even in powerful model
organisms such as Caenorhabditis elegans with controlled genetic backgrounds and …

The use of pesticides is ubiquitous worldwide, and these chemicals exert adverse effects on
both target and nontarget species. Understanding the modes of action of pesticides, as well …

Increased lifespan can be associated with greater resistance to many different stressors,
most notably thermal stress. Such hormetic effects have also been found in C. elegans …

Aging is a process of progressive decline in physiological functions resulting in increased
vulnerability to diseases and death. Aging results in increased rates of age related disorders …

The DNA transposon Tc 1 was the first transposable element to be characterized in
Caenorhabditis elegans and to date, remains the best-studied transposable element in …

The sorting nexins family of proteins (SNXs) plays pleiotropic functions in protein trafficking
and intracellular signaling and has been associated with several disorders, namely …

Plants produce promising chemicals called secondary metabolites in response to stress,
which protect against oxidative damage in both plants and humans. Reactive oxygen …