Clinical applications of fundus autofluorescence in retinal disease

M Yung, MA Klufas, D Sarraf - International journal of retina and vitreous, 2016 - Springer
Fundus autofluorescence (FAF) is a non-invasive retinal imaging modality used in clinical
practice to provide a density map of lipofuscin, the predominant ocular fluorophore, in the …

[HTML][HTML] Fundus autofluorescence and clinical applications

C Pole, H Ameri - Journal of Ophthalmic & Vision Research, 2021 - ncbi.nlm.nih.gov
Fundus autofluorescence (FAF) has allowed in vivo mapping of retinal metabolic
derangements and structural changes not possible with conventional color imaging. Incident …

Multimodal imaging in best vitelliform macular dystrophy

JRL de Carvalho, M Paavo, L Chen… - … & Visual Science, 2019 - iovs.arvojournals.org
Purpose: In patients diagnosed with Best vitelliform macular dystrophy (BVMD), quantitative
fundus autofluorescence (qAF), near-infrared fundus autofluorescence (NIR-AF), and …

[HTML][HTML] Gene therapy in bestrophinopathies: Insights from preclinical studies in preparation for clinical trials

A Amato, N Wongchaisuwat, A Lamborn… - Saudi Journal of …, 2023 - journals.lww.com
The BEST1 gene encodes bestrophin-1, a homopentameric ion channel expressed in the
retinal pigment epithelium (RPE), where it localizes to the basolateral plasma membrane …

Correlation of type 1 neovascularization associated with acquired vitelliform lesion in the setting of age-related macular degeneration

CA Curcio, C Balaratnasingam, JD Messinger… - American Journal of …, 2015 - Elsevier
Purpose To correlate postmortem histology with previously recorded multimodal imaging
from a patient with type 1 neovascularization (NV) associated with an acquired vitelliform …

Phenotypic and genetic spectrum of autosomal recessive bestrophinopathy and best vitelliform macular dystrophy

TA Pfister, WM Zein, CA Cukras… - … & Visual Science, 2021 - iovs.arvojournals.org
Purpose: Autosomal recessive bestrophinopathy (ARB) and vitelliform macular dystrophy
(VMD) are distinct phenotypes, typically inherited through recessive and dominant patterns …

Fundus autofluorescence imaging: systematic review of test accuracy for the diagnosis and monitoring of retinal conditions

GK Frampton, N Kalita, L Payne, JL Colquitt… - Eye, 2017 - nature.com
We conducted a systematic review of the accuracy of fundus autofluorescence (FAF)
imaging for diagnosing and monitoring retinal conditions. Searches in November 2014 …

[HTML][HTML] Fundus Autofluorescence in Diabetic Retinopathy

OM Dumitrescu, M Zemba… - Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Diabetic retinopathy is a leading cause of visual morbidity worldwide. Fundus
autofluorescence is a rapid, non-invasive imaging modality that has gained increased …

Pattern dystrophy: an imprecise diagnosis in the age of precision medicine

AM Hanif, J Yan, N Jain - International Ophthalmology Clinics, 2019 - journals.lww.com
Pattern dystrophies of the retinal pigment epithelium (RPE) represent a clinically
heterogeneous group of disorders characterized by distinctive configurations of macular …

Optical coherence tomography normative peripapillary retinal nerve fiber layer and macular data in children 0–5 years of age

JC Rotruck, RJ House, SF Freedman, MP Kelly… - American Journal of …, 2019 - Elsevier
Purpose To determine reference values for the peripapillary retinal nerve fiber layer
(pRNFL) and macula in children 0–5 years of age. Design Prospective cross-sectional study …