Advances in the Computational Assessment of Disturbed Coronary Flow and Wall Shear Stress: A Contemporary Review

AA Ekmejian, HJ Carpenter, JL Ciofani… - Journal of the …, 2024 - ahajournals.org
Coronary artery blood flow is influenced by various factors including vessel geometry,
hemodynamic conditions, timing in the cardiac cycle, and rheological conditions. Multiple …

Coronary artery vorticity to predict functional plaque progression in participants with type 2 diabetes mellitus

N Tomizawa, S Fujimoto, T Mita… - Radiology …, 2023 - pubs.rsna.org
Purpose To investigate whether vorticity could predict functional plaque progression better
than high-risk plaque (HRP) and lesion length (LL) in individuals with type 2 diabetes …

Blood flow energy identifies coronary lesions culprit of future myocardial infarction

M Lodi Rizzini, A Candreva, V Mazzi… - Annals of Biomedical …, 2024 - Springer
The present study establishes a link between blood flow energy transformations in coronary
atherosclerotic lesions and clinical outcomes. The predictive capacity for future myocardial …

Application of physics-based flow models in cardiovascular medicine: Current practices and challenges

M Vardhan, A Randles - Biophysics Reviews, 2021 - pubs.aip.org
Personalized physics-based flow models are becoming increasingly important in
cardiovascular medicine. They are a powerful complement to traditional methods of clinical …

Optimization of FFR prediction algorithm for gray zone by hemodynamic features with synthetic model and biometric data

HJ Lee, YW Kim, JH Kim, YJ Lee, J Moon… - Computer Methods and …, 2022 - Elsevier
Background Recent attempts on adopting artificial intelligence algorithm on coronary
diagnosis had limitations on data quantity and quality. While most of previous studies only …

The impact of the right coronary artery geometric parameters on hemodynamic performance

N Pinho, LC Sousa, CF Castro, CC António… - Cardiovascular …, 2019 - Springer
Purpose Coronary artery geometry can have a significant impact in the hemodynamic
behavior of coronary blood flow, influencing atherosclerotic plaque formation. The present …

Impact of coronary bifurcation angle on computed tomography derived fractional flow reserve in coronary vessels with no apparent coronary artery disease

T Tsugu, K Tanaka, Y Nagatomo, D Belsack… - European …, 2023 - Springer
Objectives Computed tomography (CT) derived fractional flow reserve (FFRCT) decreases
from the proximal to the distal part due to a variety of factors. The energy loss due to the …

Establishing the longitudinal hemodynamic mapping framework for wearable-driven coronary digital twins

C Tanade, NS Khan, E Rakestraw, WD Ladd… - NPJ Digital …, 2024 - nature.com
Understanding the evolving nature of coronary hemodynamics is crucial for early disease
detection and monitoring progression. We require digital twins that mimic a patient's …

Diagnostic performance of coronary angiography derived computational fractional flow reserve

M Vardhan, C Tanade, SJ Chen… - Journal of the …, 2024 - ahajournals.org
Background Computational fluid dynamics can compute fractional flow reserve (FFR)
accurately. However, existing models are limited by either the intravascular hemodynamic …

Paradoxical changes of coronary computed tomography derived fractional flow reserve

T Tsugu, K Tanaka, Y Nagatomo, D Belsack… - …, 2022 - Wiley Online Library
A total of 1335 outpatients with suspected coronary artery disease and who underwent
computed tomography derived fractional flow reserve (FFRCT) analysis were examined …