Abstract Development of a multicellular organism from a fertilized egg depends on a precise
balance between symmetric cell divisions to expand the pool of similar cells, and …

Polarity establishment, asymmetric division, and acquisition of cell fates are critical steps
during earlydevelopment. In this review, we discuss processes that set up the embryonic …

The cell division axis determines the future positions of daughter cells and is therefore
critical for cell fate. The positioning of the division axis has been mostly studied in systems …

The spatial organization of cells depends on their ability to sense their own shape and size.
Here, we investigate how cell shape affects the positioning of the nucleus, spindle and …

During unequal cell divisions a mitotic spindle is eccentrically positioned before cell
cleavage. To determine the basis of the net force imbalance that causes spindle …

The correlation between cell shape elongation and the orientation of the division axis
described by early cell biologists is still used as a paradigm in developmental studies …

The assembly and disassembly of microtubules can generate pushing and pulling forces
that, together with motor proteins, contribute to the correct positioning of chromosomes …

Proper spatial control of the cell division plane is essential to any developing organism. In
most cell types, the relative size of the two daughter cells is determined by the position of the …

Neuronal migrations along glial fibers provide a primary pathway for the formation of cortical
laminae. To examine the mechanisms underlying glial-guided migration, we analyzed the …

Correct positioning of the spindle governs placement of the cytokinesis furrow and thus
plays a crucial role in the partitioning of fate determinants and the disposition of daughter …