PI3K/AKT signaling pathway as a critical regulator of Cisplatin response in tumor cells

ZN Navaei, G Khalili-Tanha, AS Zangouei… - Oncology …, 2022 - pmc.ncbi.nlm.nih.gov
Chemotherapy is one of the main therapeutic modalities for cancer patients. Cisplatin
(CDDP), as one of the first-line drugs, is of great importance in the chemotherapy of various …

MicroRNAs as the critical regulators of cell migration and invasion in thyroid cancer

AA Hamidi, N Taghehchian, Z Basirat, AS Zangouei… - Biomarker …, 2022 - Springer
Thyroid cancer (TC) is one of the most frequent endocrine malignancies that is more
common among females. Tumor recurrence is one of the most important clinical …

Circular RNAs as the pivotal regulators of epithelial-mesenchymal transition in gastrointestinal tumor cells

RA Mahmoudian, I Akhlaghipour, M Lotfi… - … -Research and Practice, 2023 - Elsevier
Gastrointestinal (GI) cancers, as the most common human malignancies are always
considered one of the most important health challenges in the world. Late diagnosis in …

MicroRNA-377: A therapeutic and diagnostic tumor marker

I Akhlaghipour, N Taghehchian, AS Zangouei… - International journal of …, 2023 - Elsevier
Cancer is considered as one of the main causes of human deaths globally. Despite the
recent progresses in therapeutic modalities, there is still a high rate of mortality among …

MicroRNAs as the pivotal regulators of cisplatin resistance in head and neck cancers

F Tolue Ghasaban, A Maharati, AS Zangouei… - Cancer cell …, 2023 - Springer
Although, there is a high rate of good prognosis in early stage head and neck tumors, about
half of these tumors are detected in advanced stages with poor prognosis. A combination of …

PRC2 mediated KLF2 down regulation: a therapeutic and diagnostic axis during tumor progression

N Taghehchian, A Maharati, I Akhlaghipour… - Cancer Cell …, 2023 - Springer
Surgery and chemo-radiotherapy are used as the common first-line treatment options in
many cancers. However, tumor relapse is observed in many cancer patients following such …

Systematic cancer-testis gene expression analysis identified CDCA5 as a potential therapeutic target in esophageal squamous cell carcinoma

J Xu, C Zhu, Y Yu, W Wu, J Cao, Z Li, J Dai, C Wang… - …, 2019 - thelancet.com
Background Esophageal squamous cell carcinoma (ESCC) is one of the most lethal
malignancies with poor prognosis. Cancer-testis genes (CTGs) have been vigorously …

MicroRNAs as the pivotal regulators of cisplatin resistance in osteosarcoma

M Moghbeli - Pathology-Research and Practice, 2023 - Elsevier
Osteosarcoma (OS) is an aggressive bone tumor that originates from mesenchymal cells. It
is considered as the eighth most frequent childhood cancer that mainly affects the tibia and …

Role of the long non-coding RNAs in regulation of Gemcitabine response in tumor cells

A Maharati, Y Samsami, H Latifi… - Cancer cell …, 2023 - Springer
Chemotherapy is widely used as one of the first line therapeutic methods in cancer patients.
However, chemotherapeutic resistance is one of the most common problems in cancer …

Overexpressed PKMYT1 promotes tumor progression and associates with poor survival in esophageal squamous cell carcinoma

Q Zhang, X Zhao, C Zhang, W Wang, F Li… - Cancer Management …, 2019 - Taylor & Francis
Background Esophageal squamous cell carcinoma (ESCC) is one of the most common
malignant tumors worldwide and the 5-year overall survival rate remains poor. Protein …