Impact of anaesthetic drugs and adjuvants on ECG markers of torsadogenicity

C Staikou, M Stamelos… - British Journal of …, 2014 - academic.oup.com
Drug-induced prolongation of cardiac repolarization may trigger malignant ventricular
arrhythmias, such as torsade de pointes. The duration of QT interval, QT corrected for heart …

The role of Volatile Anesthetics in Cardioprotection: a systematic review

NR Van Allen, PR Krafft, AS Leitzke, RL Applegate… - Medical gas …, 2012 - Springer
This review evaluates the mechanism of volatile anesthetics as cardioprotective agents in
both clinical and laboratory research and furthermore assesses possible cardiac side effects …

[HTML][HTML] Perioperative management of patients with congenital or acquired disorders of the QT interval

M O'hare, Y Maldonado, J Munro, MJ Ackerman… - British journal of …, 2018 - Elsevier
QT prolongation can be attributable to various causes that can be categorised as acquired
or congenital. Arrhythmias related to QT prolongation can result in clinical presentations …

[HTML][HTML] Drugs to be avoided in patients with long QT syndrome: focus on the anaesthesiological management

G Fazio, F Vernuccio, G Grutta, GL Re - World journal of cardiology, 2013 - ncbi.nlm.nih.gov
Long QT syndrome incidence is increasing in general population. A careful pre-, peri-and
post-operative management is needed for patients with this syndrome because of the risk of …

Long QT syndrome and perioperative torsades de pointes: what the anesthesiologist should know

N Niimi, K Yuki, K Zaleski - Journal of Cardiothoracic and Vascular …, 2022 - jcvaonline.com
TORSADES DE pointes (TdP or “twisting of the points”) is a rare but potentially fatal
polymorphic ventricular tachycardia characterized by rapid, wide QRS complexes of …

Effects of esmolol, lidocaine and fentanyl on P wave dispersion, QT, QTc intervals and hemodynamic responses to endotracheal intubation during propofol induction …

V Hancı, S Yurtlu, T Karabağ, D Okyay… - Brazilian Journal of …, 2013 - Elsevier
Background and objectives: In our study we aimed to investigate the effect of esmolol,
lidocaine and fentanyl on P-wave dispersion (Pwd), QT and corrected QT (QTc) durations …

Preoperative abnormal P and QTc dispersion intervals in patients with metabolic syndrome

V Hanc, S Yurtlu, M Aydn, S Bilir, G Erdogan… - Anesthesia & …, 2011 - journals.lww.com
METHODS After obtaining the approval of the hospital ethics committee and written consent
from the patients, adult patients (older than 18 years) evaluated in the anesthesia …

Propofol-associated QTc prolongation

MJ Scalese, HR Herring, RC Rathbun… - … Advances in Drug …, 2016 - journals.sagepub.com
Objectives: Propofol is a preferred agent for sedation in patients in the intensive care unit
(ICU) due, in part, to its established safety profile. Despite this, recent case reports have …

[HTML][HTML] Comparison of the effects of propofol and sevoflurane on QT interval in pediatrics undergoing cochlear implantation: a randomized clinical trial study

R Safaeian, V Hassani, M Mohseni… - … and Pain Medicine, 2019 - ncbi.nlm.nih.gov
Background Children with sensorineural hearing loss are at risk of cardiac
electrophysiologic abnormalities. Inhalational Sevoflurane induction in these children can …

Propofol inhibits hERG K+ channels and enhances the inhibition effects on its mutations in HEK293 cells

SN Han, Y Jing, LL Yang, Z Zhang, LR Zhang - European Journal of …, 2016 - Elsevier
QT interval prolongation, a potential risk for arrhythmias, may result from gene
polymorphisms relevant to cardiomyocyte repolarization. Another noted cause of QT interval …