Once a biological novelty known for their role in bioluminescence, fluorescent proteins (FPs)
from marine invertebrates have revolutionized the life sciences. Organisms from all …

The chicken represents a valuable model for research in the area of immunology, infectious
diseases as well as developmental biology. Although it was the first livestock species to …

We report the first ubiquitous green fluorescent protein expression in chicks using a lentiviral
vector approach, with eGFP under the control of the phosphoglycerol kinase promoter …

The chicken has potential as an efficient bioreactor system because of its outstanding
protein production capacity and low cost. The CRISPR/Cas9-mediated gene-editing system …

Scientific research and progress, particularly in the drug discovery and regenerative
medicine fields, is typically dependent on suitable animal models to develop new and …

In this study, we confirmed the ability of the 2-kb promoter fragment of the chicken ovalbumin
gene to drive tissue-specific expression of a foreign EGFP gene in chickens. Recombinant …

Replication-defective retroviral or lentiviral vectors have been used for the production of
transgenic animals. Chicken primordial germ cells (PGCs) are the precursors for ova and …

Generating biopharmaceuticals in genetically engineered bioreactors continues to reign
supreme. Hence, genetically engineered birds have attracted considerable attention from …

Several strategies have been used to generate transgenic birds. The most successful
method so far has been the injection of lentiviral vectors into the subgerminal cavity of a …

The transgenic chicken has great potential as a bioreactor for the production of valuable
pharmaceutical proteins, notably in the oviduct/egg. Whereas conventional transgenic …