Type 1 diabetes is an autoimmune disorder in which the immune system attacks and
destroys insulin-producing islet cells of the pancreas. Although islet transplantation has …

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Transplantation of allogeneic pancreatic donor islets has successfully been performed in
selected patients with difficult-to-control insulin-dependent diabetes and impaired …

Islet transplantation to treat insulin-dependent diabetes is greatly limited by the need for
maintenance immunosuppression. We report a strategy through which cotransplantation of …

The complement and immunoglobulin receptors are the major phagocytic receptors involved
during infection. However, only immunoglobulin-dependent uptake results in a respiratory …

▪ Abstract The immune response is regulated not only by cell proliferation and differentiation,
but also by programmed cell death, or apoptosis. In response to various stimuli, death …

Malignant melanoma accounts for most of the increasing mortality from skin cancer.
Melanoma cells were found to express Fas (also called Apo-1 or CD95) ligand (FasL). In …

Islet transplantation is a promising therapy for type 1 diabetes. However, chronic
immunosuppression to control rejection of allogeneic islets induces morbidities and impairs …

Cells of the dendritic family display some unique properties that confer to them the capacity
to sensitize naive T cells in vitro and in vivo. In the mouse, two subclasses of dendritic cells …

▪ Abstract Apoptosis of mature T lymphocytes preserves peripheral homeostasis and
tolerance by countering the profound changes in the number and types of T cells stimulated …