Zebrafish cancer avatars: A translational platform for analyzing tumor heterogeneity and predicting patient outcomes

MA Al-Hamaly, LT Turner, A Rivera-Martinez… - International Journal of …, 2023 - mdpi.com
The increasing number of available anti-cancer drugs presents a challenge for oncologists,
who must choose the most effective treatment for the patient. Precision cancer medicine …

Recent development in zebrafish model for bioactivity and safety evaluation of natural products

FJ Lin, H Li, DT Wu, QG Zhuang, HB Li… - Critical Reviews in …, 2022 - Taylor & Francis
The zebrafish is a species of freshwater fish, popular in aquariums and laboratories. Several
advantageous features have facilitated zebrafish to be extensively utilized as a valuable …

Single-cell imaging of T cell immunotherapy responses in vivo

C Yan, Q Yang, S Zhang, DG Millar, EJ Alpert… - Journal of Experimental …, 2021 - rupress.org
T cell immunotherapies have revolutionized treatment for a subset of cancers. Yet, a major
hurdle has been the lack of facile and predicative preclinical animal models that permit …

Zebrafish models for the safety and therapeutic testing of nanoparticles with a focus on macrophages

A Pensado-López, J Fernández-Rey, P Reimunde… - Nanomaterials, 2021 - mdpi.com
New nanoparticles and biomaterials are increasingly being used in biomedical research for
drug delivery, diagnostic applications, or vaccines, and they are also present in numerous …

Cellular and molecular mechanisms underlying glioblastoma and zebrafish models for the discovery of new treatments

P Reimunde, A Pensado-López, M Carreira Crende… - Cancers, 2021 - mdpi.com
Simple Summary Glioblastoma (GBM) is one of the greatest challenges facing neuro-
oncology today. Current treatments are far from satisfactory and, given the poor prognosis of …

Zebrafish—A Suitable Model for Rapid Translation of Effective Therapies for Pediatric Cancers

D Roy, B Subramaniam, WC Chong, M Bornhorst… - Cancers, 2024 - mdpi.com
Simple Summary Cancer stands as the leading cause of death among children and
adolescents in the United States. Some of these pediatric cancers are highly aggressive and …

Zebrafish models of paediatric brain tumours

F Basheer, P Dhar, RM Samarasinghe - International Journal of …, 2022 - mdpi.com
Paediatric brain cancer is the second most common childhood cancer and is the leading
cause of cancer-related deaths in children. Despite significant advancements in the …

A new" single" era of biomedicine and implications in disease research

C Hu - Journal of Bio-X Research, 2023 - spj.science.org
In recent decades, single-cell (SC) technologies and applications have been a very hot
topics in the field of biology and medicine. In fact, early studies involving a single cell were …

“Fishing” nano–bio interactions at the key biological barriers

J Rong, Y He, J Tang, R Qiao, S Lin - Nanoscale, 2021 - pubs.rsc.org
Understanding nano–bio interactions is pivotal to the safe implementation of
nanotechnology for both biological and environmental applications. Zebrafish as a model …

Bioluminescent zebrafish transplantation model for drug discovery

M Hason, J Jovicic, I Vonkova, M Bojic… - Frontiers in …, 2022 - frontiersin.org
In the last decade, zebrafish have accompanied the mouse as a robust animal model for
cancer research. The possibility of screening small-molecule inhibitors in a large number of …