A narrative review of the antitumor activity of monoterpenes from essential oils: An update

TQ Machado, ACC Da Fonseca… - BioMed research …, 2022 - Wiley Online Library
Monoterpenes are a group of natural products that have been widely studied due to their
therapeutic potential against various pathologies. These compounds are abundant in the …

Ethnobotanical, pharmacological, phytochemical, and clinical investigations on Moroccan medicinal plants traditionally used for the management of renal dysfunctions

B Noureddine, E Mostafa, SC Mandal - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance Renal disease is a significant public health concern that
affects people all over the world. The main limitations of conventional therapy are the …

Importance of thymoquinone, sulforaphane, phloretin, and epigallocatechin and their health benefits

MH Shahrajabian, W Sun - Letters in Drug Design & Discovery, 2024 - benthamdirect.com
Natural products have a broad diversity of multidimensional chemical formations, which play
an important role, and indicate the crucial nature as a golden source for gaining herbal drug …

Therapeutic perspectives of the black cumin component thymoquinone: A review

C Sarkar, S Jamaddar, T Islam, M Mondal, MT Islam… - Food & Function, 2021 - pubs.rsc.org
The dietary phytochemical thymoquinone (TQ), belonging to the family of quinones, mainly
obtained from the black and angular seeds of Nigella sativa, is one of the promising …

[HTML][HTML] Chemopreventive and anticancer effects of thymoquinone: cellular and molecular targets

R Gomathinayagam, JH Ha, M Jayaraman… - Journal of cancer …, 2020 - ncbi.nlm.nih.gov
Thymoquinone (TQ) is a bioactive component derived from the seeds of Nigella sativa that
are commonly as black cumin. Evidences indicate that the medicinal properties of TQ have …

Natural products and derivatives in renal, urothelial and testicular cancers: targeting signaling pathways and therapeutic potential

D Li, J Wang, Z Tuo, KH Yoo, Q Yu, A Miyamoto… - Phytomedicine, 2024 - Elsevier
Background: Natural products have demonstrated significant potential in cancer drug
discovery, particularly in renal cancer (RCa), urothelial carcinoma (UC), and testicular …

Thymoquinone: a tie-breaker in SARS-CoV2-infected cancer patients?

S Elgohary, AA Elkhodiry, NS Amin, U Stein… - Cells, 2021 - mdpi.com
Since the beginning of the SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2)
pandemic, a race to develop a vaccine has been initiated, considering the massive and …

Impact of the APE1 redox function inhibitor E3330 in non-small cell lung cancer cells exposed to cisplatin: increased cytotoxicity and impairment of cell migration and …

R Manguinhas, AS Fernandes, JG Costa, N Saraiva… - Antioxidants, 2020 - mdpi.com
Elevated expression levels of the apurinic/apyrimidinic endonuclease 1 (APE1) have been
correlated with the more aggressive phenotypes and poor prognosis of non-small cell lung …

Recent findings on thymoquinone and its applications as a nanocarrier for the treatment of cancer and rheumatoid arthritis

RR Pal, V Rajpal, P Singh, SA Saraf - Pharmaceutics, 2021 - mdpi.com
Cancer causes a considerable amount of mortality in the world, while arthritis is an
immunological dysregulation with multifactorial pathogenesis including genetic and …

Combinatorial chemosensitive nanomedicine approach for the treatment of breast cancer

P Gupta, YR Neupane, S Parvez… - Current Molecular …, 2023 - benthamdirect.com
Breast cancer is the most commonly diagnosed type of cancer and ranks second among
cancer that leads to death. From becoming the foremost reason for global concern, this …