Oxidative stress has been implicated in tumorigenic, cardiovascular, neuro-, and age-related
degenerative changes. Antioxidants minimize the oxidative damage through neutralization …

Highlights•Ultradeformable vesicles are an advanced version of conventional lipid vesicles
having extensive flexibility.•Edge activators are a chief component for improving flexibility …

Transdermal administration of chemotherapeutics into tumor tissues may be an effective
treatment to reduce toxic side effects and improve patient compliance for melanoma. Herein …

Ocular drug delivery presents significant challenges due to various anatomical and
physiological barriers. Ultradeformable vesicles have emerged as better vesicular systems …

Aim The aim of this manuscript was to fabricate agomelatine (AGM) loaded elastosomes to
improve its corneal permeation and ocular bioavailability. AGM is a biopharmaceutical …

The study aims to improve the ocular delivery of Nebivolol HCL (NBV) belonging to the
Biopharmaceutics classification system (BCSII) by using spanlastic nanovesicles (SNVs) for …

Skin cancer poses a significant global health concern necessitating innovative treatment
approaches. This review explores the potential of vesicle nanoformulation incorporating EA …

Spanlastics, which are commonly referred to as elastic niosomes, presents a modified
advancement in the area of colloidal system based drug delivery carriers. They are different …

The objective of the current study was to fabricate a thermosensitive in situ gelling system for
the ocular delivery of carvedilol-loaded spanlastics (CRV-SPLs). In situ gel formulations …

Background/Objectives: The demand for a safe compound for hyperpigmentation is
continuously increasing. Bioactive compounds such as thymoquinone (TQ) and ascorbic …