Immune-mediated neuropathies: pathophysiology and management

A Shastri, A Al Aiyan, U Kishore… - International journal of …, 2023 - mdpi.com
Dysfunction of the immune system can result in damage of the peripheral nervous system.
The immunological mechanisms, which include macrophage infiltration, inflammation and …

Novel immunological and therapeutic insights in Guillain-Barré syndrome and CIDP

L Querol, C Lleixà - Neurotherapeutics, 2021 - Springer
Inflammatory neuropathies are a heterogeneous group of rare diseases of the peripheral
nervous system that include acute and chronic diseases, such as Guillain-Barré syndrome …

European Academy of Neurology/Peripheral Nerve Society guideline on diagnosis and treatment of chronic inflammatory demyelinating polyradiculoneuropathy …

PYK Van den Bergh, PA van Doorn… - Journal of the …, 2021 - Wiley Online Library
To revise the 2010 consensus guideline on chronic inflammatory demyelinating
polyradiculoneuropathy (CIDP). Seventeen disease experts, a patient representative, and …

Clinical and laboratory features in anti-NF155 autoimmune nodopathy

L Martín-Aguilar, C Lleixà, E Pascual-Goñi… - Neurology …, 2021 - AAN Enterprises
Background and Objectives To study the clinical and laboratory features of antineurofascin-
155 (NF155)–positive autoimmune nodopathy (AN). Methods Patients with anti-NF155 …

[HTML][HTML] Therapeutic monoclonal antibody therapies in chronic autoimmune demyelinating neuropathies

C Briani, A Visentin - Neurotherapeutics, 2022 - Elsevier
Autoimmune diseases of the peripheral nervous system have so far been treated mainly with
exogenous high-dose intravenous immunoglobulins (IVIg), that act through several …

Peripheral nervous system (PNS) myelin diseases

SS Scherer, J Svaren - Cold Spring Harbor Perspectives …, 2024 - cshperspectives.cshlp.org
This is a review of inherited and acquired causes of human demyelinating neuropathies and
a subset of disorders that affect axon–Schwann cell interactions. Nearly all inherited …

Bruton's tyrosine kinase-bearing B cells and microglia in neuromyelitis optica spectrum disorder

Y Liu, Z Huang, TX Zhang, B Han, G Yang, D Jia… - Journal of …, 2023 - Springer
Background Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory
autoimmune disease of the central nervous system that involves B-cell receptor signaling as …

Anti-pan-neurofascin antibodies induce subclass-related complement activation and nodo-paranodal damage

L Appeltshauser, H Junghof, J Messinger, J Linke… - Brain, 2023 - academic.oup.com
Autoimmune neuropathy associated with antibodies against pan-neurofascin is a new
subtype of nodo-paranodopathy. It is relevant because it is associated with high morbidity …

Autoimmune nodopathies, an emerging diagnostic category

L Martín-Aguilar, C Lleixà… - Current Opinion in …, 2022 - journals.lww.com
AN have emerged as a new diagnostic category pathologically different from acquired
demyelinating neuropathies. Clinically they overlap with GBS and CIDP although they …

[HTML][HTML] The role of the complement system in chronic inflammatory demyelinating polyneuropathy: implications for complement-targeted therapies

LA Querol, HP Hartung, RA Lewis, PA van Doorn… - …, 2022 - Elsevier
Chronic inflammatory demyelinating polyneuropathy (CIDP) is the most common,
heterogeneous, immune-mediated neuropathy, characterized by predominant …