The physics of respiratory particle generation, fate in the air, and inhalation

L Morawska, G Buonanno, A Mikszewski… - Nature Reviews …, 2022 - nature.com
Given that breathing is one of the most fundamental physiological functions, there is an
urgent need to broaden our understanding of the fluid dynamics that governs it. There would …

Mechanisms of pharmaceutical aerosol deposition in the respiratory tract

YS Cheng - AAPS pharmscitech, 2014 - Springer
Aerosol delivery is noninvasive and is effective in much lower doses than required for oral
administration. Currently, there are several types of therapeutic aerosol delivery systems …

Comparison of micro-and nano-size particle depositions in a human upper airway model

Z Zhang, C Kleinstreuer, JF Donohue, CS Kim - Journal of aerosol science, 2005 - Elsevier
Simulation results of microparticle and nanoparticle deposition patterns, local
concentrations, and segmental averages are contrasted for a human upper airway model …

Targeted drug-aerosol delivery in the human respiratory system

C Kleinstreuer, Z Zhang… - Annu. Rev. Biomed. Eng., 2008 - annualreviews.org
Inhalation of drug aerosols is a modern pathway to combat lung diseases. It is also
becoming the preferred route for insulin delivery, pain management, cancer therapy, and …

Aerosol deposition in the extrathoracic region

YS Cheng - Aerosol Science & Technology, 2003 - Taylor & Francis
The extrathoracic region, including the nasal and oral passages, pharynx, and larynx, is the
entrance to the human respiratory tract and the first line of defense against inhaled air …

[图书][B] Occupational lung diseases.

WKC Morgan, A Seaton - 1975 - cabidigitallibrary.org
The authors state in their preface that this book was designed mainly to assist the practising
clinician, including the pathologist and radiologist, to keep in touch with the changes in the …

In vitro intersubject and intrasubject deposition measurements in realistic mouth–throat geometries

B Grgic, WH Finlay, PKP Burnell, AF Heenan - Journal of Aerosol Science, 2004 - Elsevier
This paper presents regional and total deposition measurements in several realistic mouth
and throat geometries and demonstrates the effects of intrasubject and intersubject …

Pulmonary aerosol transport and deposition analysis in upper 17 generations of the human respiratory tract

MS Islam, SC Saha, E Sauret, T Gemci, YT Gu - Journal of Aerosol Science, 2017 - Elsevier
The major problem in understanding the therapeutically targeted drug delivery system in the
deeper airways of the human lung is the lack of adequate data of particle transport and …

Regional aerosol deposition and flow measurements in an idealized mouth and throat

B Grgic, WH Finlay, AF Heenan - Journal of Aerosol Science, 2004 - Elsevier
Extrathoracic deposition was studied using an idealized average human mouth and throat
replica. Effects of particle size, flow rate and flow Reynolds number were examined using …

Micro-particle transport and deposition in a human oral airway model

Z Zhang, C Kleinstreuer, CS Kim - Journal of Aerosol Science, 2002 - Elsevier
Laminar-to-turbulent air flow for typical inhalation modes as well as micro-particle transport
and wall deposition in a representative human oral airway model have been simulated …