Since the discovery of AMP-activated protein kinase (AMPK) as a central regulator of energy
homeostasis, many exciting insights into its structure, regulation and physiological roles …

The contention that brown adipose tissue is absent in adult man has meant that processes
attributed to active brown adipose tissue in experimental animals (mainly rodents), ie …

The role of AMP-activated protein kinase (AMPK) in promoting fatty acid (FA) oxidation in
various tissues, such as liver and muscle, has been well understood. However, the role of …

AMP-activated protein kinase (AMPK) has a major role in the modulation of energy balance.
AMPK is activated in conditions of low energy, increasing energy production and reducing …

Abstract Purpose of Review The global prevalence of type 2 diabetes (T2D) is escalating at
alarming rates, demanding the development of additional classes of therapeutics to further …

AMPK (AMP-activated protein kinase) is a key regulator of cellular and whole-body energy
balance. AMPK phosphorylates and regulates many proteins concerned with nutrient …

Recent advances have been made in the understanding of pharmacological and dietary
agents that contribute to browning of white adipose tissue in order to combat obesity by …

The incidence of the metabolic syndrome has reached epidemic levels in the Western world.
With respect to the energy balance, most attention has been given to reducing energy (food) …

The adipocyte is like a bank: a place to store excess (caloric) cash in times of plenty, and
from which one can withdraw savings during “lean times.” The β-adrenoceptors (βAR) are …

The evolutionarily conserved serine/threonine kinase, AMP‐activated protein kinase
(AMPK), functions as a cellular fuel gauge that regulates metabolic pathways in glucose and …