Global trends in hepatocellular carcinoma epidemiology: implications for screening, prevention and therapy
Hepatocellular carcinoma (HCC) mortality rates are increasing globally, and particularly in
the Western world. Cirrhosis remains the predominant risk factor for HCC. However …
the Western world. Cirrhosis remains the predominant risk factor for HCC. However …
Hepatocellular carcinoma (primer)
JM Llovet, RK Kelley, A Villanueva… - Nature Reviews …, 2021 - search.proquest.com
Liver cancer remains a global health challenge, with an estimated incidence of> 1 million
cases by 2025. Hepatocellular carcinoma (HCC) is the most common form of liver cancer …
cases by 2025. Hepatocellular carcinoma (HCC) is the most common form of liver cancer …
AASLD practice guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma
This guidance document provides an updated approach to the prevention, diagnosis, and
treatment of hepatocellular carcinoma (HCC). The prior American Association for the Study …
treatment of hepatocellular carcinoma (HCC). The prior American Association for the Study …
Intratumoral dendritic cell–CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma
Despite no apparent defects in T cell priming and recruitment to tumors, a large subset of T
cell rich tumors fail to respond to immune checkpoint blockade (ICB). We leveraged a …
cell rich tumors fail to respond to immune checkpoint blockade (ICB). We leveraged a …
Perioperative nivolumab monotherapy versus nivolumab plus ipilimumab in resectable hepatocellular carcinoma: a randomised, open-label, phase 2 trial
Background Hepatocellular carcinoma has high recurrence rates after surgery; however,
there are no approved standard-of-care neoadjuvant or adjuvant therapies. Immunotherapy …
there are no approved standard-of-care neoadjuvant or adjuvant therapies. Immunotherapy …
A global view of hepatocellular carcinoma: trends, risk, prevention and management
Hepatocellular carcinoma (HCC) is the fourth most common cause of cancer-related death
worldwide. Risk factors for HCC include chronic hepatitis B and hepatitis C, alcohol …
worldwide. Risk factors for HCC include chronic hepatitis B and hepatitis C, alcohol …
NAFLD-driven HCC: Safety and efficacy of current and emerging treatment options
In light of a global rise in obesity and type 2 diabetes, non-alcoholic fatty liver disease
(NAFLD) and non-alcoholic steatohepatitis (NASH) represent an increasingly important …
(NAFLD) and non-alcoholic steatohepatitis (NASH) represent an increasingly important …
Hepatocellular carcinoma: old friends and new tricks
E Kim, P Viatour - Experimental & molecular medicine, 2020 - nature.com
Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer and a leading
cause of cancer-related deaths worldwide. Ninety percent of HCC cases arise from cirrhosis …
cause of cancer-related deaths worldwide. Ninety percent of HCC cases arise from cirrhosis …
Apatinib as second-line or later therapy in patients with advanced hepatocellular carcinoma (AHELP): a multicentre, double-blind, randomised, placebo-controlled …
S Qin, Q Li, S Gu, X Chen, L Lin, Z Wang… - The lancet …, 2021 - thelancet.com
Background Inhibition of vascular endothelial growth factor receptor (VEGFR) has shown
antitumour activity in advanced hepatocellular carcinoma, but few studies of VEGFR …
antitumour activity in advanced hepatocellular carcinoma, but few studies of VEGFR …
Diagnosis, staging, and management of hepatocellular carcinoma: 2018 practice guidance by the American Association for the Study of Liver Diseases
This guidance provides a data-supported approach to the diagnosis, staging, and treatment
of patients diagnosed with hepatocellular carcinoma (HCC). A guidance document is …
of patients diagnosed with hepatocellular carcinoma (HCC). A guidance document is …