Foam cell formation and further accumulation in the subendothelial space of the vascular
wall is a hallmark of atherosclerotic lesions. Targeting foam cell formation in the …

Introduction• Current concepts in monocyte heterogeneity• Pro‐atherogenic role of plaque
macrophages• Anti‐atherogenic role of plaque macrophages• Macrophage heterogeneity …

The recent failure of candidate drugs like cholesterol ester transfer protein (CETP) and acyl-
CoA: cholesterol acyltransferase (ACAT) inhibitors calls for a revised approach for screening …

Atherosclerosis is now recognised as a chronic inflammatory disease occurring within the
artery wall and ultimately responsible for myocardial infarction, stroke and peripheral …

Objective: Coronary artery diseases including myocardial ischemia (MI) remain one of the
leading causes of death worldwide. This study was designed to compare the protective …

Background Atherosclerotic plaque rupture is the primary mechanism of thrombosis which
plays a key role in the onset of acute coronary syndromes. Detection of these plaques prone …

Background This study investigated the inhibitory effect of berberine (BBR) on
lipopolysaccharide (LPS) induced cyclooxygenase-2 (COX-2) expression via the mitogen …

Aim Millions of people die each year due to cardiovascular disease (CVD). A Western
lifestyle not only fuses a significant intake of fat with physical inactivity and obesity but also …