Detecting biothreat agents: From current diagnostics to developing sensor technologies

SA Walper, G Lasarte Aragonés, KE Sapsford… - ACS …, 2018 - ACS Publications
Although a fundamental understanding of the pathogenicity of most biothreat agents has
been elucidated and available treatments have increased substantially over the past …

Microfluidic devices for DNA sequencing: sample preparation and electrophoretic analysis

BM Paegel, RG Blazej, RA Mathies - Current opinion in biotechnology, 2003 - Elsevier
Modern DNA sequencing 'factories' have revolutionized biology by completing the human
genome sequence, but in the race to completion we are left with inefficient, cumbersome …

Microfabricated 384-lane capillary array electrophoresis bioanalyzer for ultrahigh-throughput genetic analysis

CA Emrich, H Tian, IL Medintz, RA Mathies - Analytical Chemistry, 2002 - ACS Publications
A microfabricated 384-lane capillary array electrophoresis device is developed and utilized
for massively parallel genetic analysis. The 384 capillary lanes, arrayed radially about the …

[图书][B] Bio-MEMS: technologies and applications

W Wang, SA Soper - 2006 - taylorfrancis.com
Microelectromechanical systems (MEMS) are evolving into highly integrated technologies
for a variety of application areas. Add the biological dimension to the mix and a host of new …

High throughput DNA sequencing with a microfabricated 96-lane capillary array electrophoresis bioprocessor

BM Paegel, CA Emrich… - Proceedings of the …, 2002 - National Acad Sciences
High throughput DNA sequencing has been performed by using a microfabricated 96-
channel radial capillary array electrophoresis (μCAE) microchannel plate detected by a 4 …

[图书][B] Microfluidic lab-on-a-chip for chemical and biological analysis and discovery

PCH Li - 2005 - taylorfrancis.com
The microfluidic lab-on-a-chip allows scientists to conduct chemical and biochemical
analysis in a miniaturized format so small that properties and effects are successfully …

DNA sequencing and genotyping in miniaturized electrophoresis systems

CW Kan, CP Fredlake, EAS Doherty… - Electrophoresis, 2004 - Wiley Online Library
Advances in microchannel electrophoretic separation systems for DNA analyses have had
important impacts on biological and biomedical sciences, as exemplified by the successes …

Electrophoresis: the march of pennies, the march of dimes

PG Righetti - Journal of Chromatography A, 2005 - Elsevier
The present review encompasses ca. 65 years of history of developments in electrokinetic
separations, taking as a starting point the year 1937, ie the official launching of Tiselius' …

Microchip bioprocessor for integrated nanovolume sample purification and DNA sequencing

BM Paegel, SHI Yeung, RA Mathies - Analytical Chemistry, 2002 - ACS Publications
A microfabricated electrophoretic bioprocessor for integrated DNA sequencing sample
desalting, template removal, preconcentration, and CE analysis is presented. A low-viscosity …

Disposable roll-to-roll hot embossed electrophoresis chip for detection of antibiotic resistance gene mecA in bacteria

R Liedert, LK Amundsen, A Hokkanen, M Mäki… - Lab on a Chip, 2012 - pubs.rsc.org
We present a high-throughput roll-to-roll (R2R) manufacturing process for foil-based
polymethyl methacrylate (PMMA) chips of excellent optical quality. These disposable, R2R …