Molecular Mechanisms of Drug Resistance in Staphylococcus aureus

B Mlynarczyk-Bonikowska, C Kowalewski… - International journal of …, 2022 - mdpi.com
This paper discusses the mechanisms of S. aureus drug resistance including:(1)
introduction.(2) resistance to beta-lactam antibiotics, with particular emphasis on the mec …

Emerging resistance mechanisms for 4 types of common anti-MRSA antibiotics in Staphylococcus aureus: A comprehensive review

WT Liu, EZ Chen, L Yang, C Peng, Q Wang, Z Xu… - Microbial …, 2021 - Elsevier
Staphylococcus aureus is one of the leading hospital-associated and community-associated
pathogens, which has caused a global public health concern. The emergence of methicillin …

β-Lactams against the Fortress of the Gram-Positive Staphylococcus aureus Bacterium

JF Fisher, S Mobashery - Chemical reviews, 2020 - ACS Publications
The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …

[HTML][HTML] Perspectives on systematic generation of antibiotic resistance with special emphasis on modern antibiotics

IK Kavya, N Kochhar, A Ghosh, S Shrivastava… - Total Environment …, 2023 - Elsevier
Antibiotics, considered a “wonder medication” in the 20th century, have been exploited to
such an extent that bacteria have developed resistance against them giving rise to highly …

Molecular Determinants of β-Lactam Resistance in Methicillin-Resistant Staphylococcus aureus (MRSA): An Updated Review

H Lade, JS Kim - Antibiotics, 2023 - mdpi.com
The development of antibiotic resistance in Staphylococcus aureus, particularly in methicillin-
resistant S. aureus (MRSA), has become a significant health concern worldwide. The …

[HTML][HTML] Mechanism of staphylococcal resistance to clinically relevant antibiotics

D Brdová, T Ruml, J Viktorová - Drug Resistance Updates, 2024 - Elsevier
Staphylococcus aureus, a notorious pathogen with versatile virulence, poses a significant
challenge to current antibiotic treatments due to its ability to develop resistance mechanisms …

Bioactive thiazine and benzothiazine derivatives: green synthesis methods and their medicinal importance

SL Badshah, A Naeem - Molecules, 2016 - mdpi.com
Thiazines are a group of heterocyclic organic compounds that are still largely unexplored for
their pharmacological activities. There are different available methods for the synthesis of …

Rapid metagenomic next-generation sequencing during an investigation of hospital-acquired human parainfluenza virus 3 infections

AL Greninger, DM Zerr, X Qin, AL Adler… - Journal of Clinical …, 2017 - Am Soc Microbiol
Metagenomic next-generation sequencing (mNGS) is increasingly used for the unbiased
detection of viruses, bacteria, fungi, and eukaryotic parasites in clinical samples. Whole …

Antimicrobial and antibiofilm potential of bacteriocin loaded nano-vesicles functionalized with rhamnolipids against foodborne pathogens

T Niaz, S Shabbir, T Noor, M Imran - Lwt, 2019 - Elsevier
Synthetic lipid membranes are considered as promising food-grade nano vesicles (NVs), but
their functionalization is required to empower them as active-nano vesicle systems. In this …

High-level resistance of Staphylococcus aureus to β-lactam antibiotics mediated by penicillin-binding protein 4 (PBP4)

SM Hamilton, JAN Alexander, EJ Choo… - Antimicrobial agents …, 2017 - Am Soc Microbiol
ABSTRACT Penicillin-binding protein 4 (PBP4), a nonessential, low-molecular-weight
penicillin-binding protein of Staphylococcus aureus, has been implicated in low-level …