Molecular and evolutionary processes generating variation in gene expression

MS Hill, P Vande Zande, PJ Wittkopp - Nature Reviews Genetics, 2021 - nature.com
Heritable variation in gene expression is common within and between species. This
variation arises from mutations that alter the form or function of molecular gene regulatory …

Finding the genomic basis of local adaptation: pitfalls, practical solutions, and future directions

S Hoban, JL Kelley, KE Lotterhos… - The American …, 2016 - journals.uchicago.edu
Uncovering the genetic and evolutionary basis of local adaptation is a major focus of
evolutionary biology. The recent development of cost-effective methods for obtaining high …

Genetics of adaptation

K Bomblies, CL Peichel - Proceedings of the National …, 2022 - National Acad Sciences
The rediscovery of Mendel's work showing that the heredity of phenotypes is controlled by
discrete genes was followed by the reconciliation of Mendelian genetics with evolution by …

[图书][B] Eco-evolutionary dynamics

AP Hendry - 2017 - degruyter.com
In recent years, scientists have realized that evolution can occur on timescales much shorter
than the" long lapse of ages" emphasized by Darwin—in fact, evolutionary change is …

The genomic substrate for adaptive radiation in African cichlid fish

D Brawand, CE Wagner, YI Li, M Malinsky, I Keller… - Nature, 2014 - nature.com
Cichlid fishes are famous for large, diverse and replicated adaptive radiations in the Great
Lakes of East Africa. To understand the molecular mechanisms underlying cichlid …

Breaking RAD: An evaluation of the utility of restriction site‐associated DNA sequencing for genome scans of adaptation

DB Lowry, S Hoban, JL Kelley, KE Lotterhos, LK Reed… - 2017 - Wiley Online Library
Understanding how and why populations evolve is of fundamental importance to molecular
ecology. Restriction site‐associated DNA sequencing (RAD seq), a popular reduced …

Genomics and the origin of species

O Seehausen, RK Butlin, I Keller, CE Wagner… - Nature Reviews …, 2014 - nature.com
Speciation is a fundamental evolutionary process, the knowledge of which is crucial for
understanding the origins of biodiversity. Genomic approaches are an increasingly …

[HTML][HTML] Common disease is more complex than implied by the core gene omnigenic model

NR Wray, C Wijmenga, PF Sullivan, J Yang… - Cell, 2018 - cell.com
The evidence that most adult-onset common diseases have a polygenic genetic architecture
fully consistent with robust biological systems supported by multiple back-up mechanisms is …

The genetic causes of convergent evolution

DL Stern - Nature Reviews Genetics, 2013 - nature.com
The evolution of phenotypic similarities between species, known as convergence, illustrates
that populations can respond predictably to ecological challenges. Convergence often …

Field-effect tunneling transistor based on vertical graphene heterostructures

L Britnell, RV Gorbachev, R Jalil, BD Belle, F Schedin… - Science, 2012 - science.org
An obstacle to the use of graphene as an alternative to silicon electronics has been the
absence of an energy gap between its conduction and valence bands, which makes it …