Alcohol use and dementia: new research directions

R Visontay, RT Rao, L Mewton - Current opinion in psychiatry, 2021 - journals.lww.com
Future research would benefit from greater implementation of analytical and design-based
approaches to robustly model the alcohol use-dementia relationship in the general …

Innate immune activation: Parallels in alcohol use disorder and Alzheimer's disease

A Ramos, RS Joshi, G Szabo - Frontiers in molecular neuroscience, 2022 - frontiersin.org
Alcohol use disorder is associated with systemic inflammation and organ dysfunction
especially in the liver and the brain. For more than a decade, studies have highlighted …

A neural circuit for alcohol withdrawal–induced hyperalgesia in a nondependent state

XL Yang, W Gao, WY Dong, C Zheng, S Wang… - Science …, 2024 - science.org
Alcohol use disorder is highly prevalent worldwide, with characteristically severe pain
sensitivity during withdrawal. Here, we established a mouse model of hyperalgesia during …

Role of mTOR‐regulated autophagy in spine pruning defects and memory impairments induced by binge‐like ethanol treatment in adolescent mice

M Pascual, R López‐Hidalgo… - Brain …, 2021 - Wiley Online Library
Adolescence is a brain maturation developmental period during which remodeling and
changes in synaptic plasticity and neural connectivity take place in some brain regions …

Alcohol and periodontal disease: A narrative review

UH Gandhi, A Benjamin, S Gajjar, T Hirani, K Desai… - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
The scientific literature dealing with alcohol and alcoholic beverages revealed that these
drinks possess an adverse impact on periodontal tissues. Additionally, other principal risk …

Unraveling the complex relationship between prenatal alcohol exposure, hippocampal LTP, and learning and memory

M Goncalves-Garcia, DA Hamilton - Frontiers in Molecular …, 2024 - frontiersin.org
Prenatal alcohol exposure (PAE) has been extensively studied for its profound impact on
neurodevelopment, synaptic plasticity, and cognitive outcomes. While PAE, particularly at …

Ethanol's impact on the brain: a neurobiological perspective on the mechanisms of memory impairment

M Hedayati-Moghadam, F Razazpour… - Molecular Biology …, 2024 - Springer
Alcohol consumption is known to have detrimental effects on memory function, with various
studies implicating ethanol in the impairment of cognitive processes related to memory …

Neurosteroid [3α, 5α]-3-Hydroxy-pregnan-20-one Enhances the CX3CL1-CX3CR1 Pathway in the Brain of Alcohol-Preferring Rats with Sex-Specificity

I Balan, A Grusca, SL Chéry, BR Materia, TK O'Buckley… - Life, 2024 - pmc.ncbi.nlm.nih.gov
This study investigates the impact of allopregnanolone ([3α, 5α] 3-hydroxypregnan-20-one
or 3α, 5α-tetrahydroprogesterone (3α, 5α-THP); 10 mg/kg, IP) on fractalkine/CX3-C motif …

Dichrocephala integrifolia Aqueous Extract Antagonises Chronic and Binges Ethanol Feeding‐Induced Memory Dysfunctions: Insights into Antioxidant and Anti …

B Yuwong Wanyu, N Emégam Kouémou… - Evidence‐Based …, 2022 - Wiley Online Library
Ethanol consumption is widely accepted despite its addictive properties and its mind‐
altering effects. This study aimed to assess the effects of Dichrocephala integrifolia against …

[HTML][HTML] Schedule-induced alcohol intake during adolescence sex dependently impairs hippocampal synaptic plasticity and spatial memory

AB Sanz-Martos, E Fuentes-Verdugo, B Merino… - Behavioural brain …, 2023 - Elsevier
In a previous study, we demonstrated that intermittent ethanol administration in male
adolescent animals impaired hippocampus-dependent spatial memory, particularly under …