We have performed a systematic review to summarize current knowledge concerning factors
related to survival in ALS and to evaluate the implications of these data for clinical trials …

Objective: To systematically review evidence bearing on the management of patients with
amyotrophic lateral sclerosis (ALS). Methods: The authors analyzed studies from 1998 to …

Amyotrophic Lateral Sclerosis (ALS) is being redefined as a distal axonopathy, in that many
molecular changes influencing motor neuron degeneration occur at the neuromuscular …

Background: We conducted a prospective, population based study to examine trends in
incidence and prevalence of amyotrophic lateral sclerosis (ALS) in Ireland from 1995 to …

Background Enteral feeding (tube feeding) is offered to many people with amyotrophic
lateral sclerosis/motor neuron disease experiencing difficulty swallowing (dysphagia) and …

Background Diaphragm movement is essential for adequate ventilation, and when the
diaphragm is adversely affected patients face lifelong positive-pressure mechanical …

BACKGROUND: Percutaneous endoscopic gastrostomy (PEG) is offered to amyotrophic
lateral sclerosis (ALS) patients with severe dysphagia. Immediate benefits of PEG are …

Amyotrophic lateral sclerosis (ALS) is a progressive neurological disease with high risk of
malnutrition. Symptoms of dysphagia, depression, cognitive impairment, difficulty with self …

Objective: We performed a prospective study of amyotrophic lateral sclerosis (ALS) in North
Canterbury, New Zealand, from 1985 to 2006, to ascertain the incidence of ALS over that 22 …

The case of Terri Schiavo resulted in substantial media attention about the use of artificial
nutrition and hydration (ANH) especially by percutaneous endoscopic gastrostomy (PEG). In …